3pre: Difference between revisions
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[[Image:3pre.png|left|200px]] | [[Image:3pre.png|left|200px]] | ||
{{STRUCTURE_3pre| PDB=3pre | SCENE= }} | {{STRUCTURE_3pre| PDB=3pre | SCENE= }} | ||
===Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors.=== | ===Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors.=== | ||
{{ABSTRACT_PUBMED_21269826}} | {{ABSTRACT_PUBMED_21269826}} | ||
==About this Structure== | ==About this Structure== | ||
[[3pre]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PRE OCA]. | [[3pre]] is a 1 chain structure of [[Phosphoinositide 3-Kinases]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PRE OCA]. | ||
==See Also== | |||
*[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:021269826</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]] | [[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]] | ||
| Line 28: | Line 20: | ||
[[Category: Knighton, D R.]] | [[Category: Knighton, D R.]] | ||
[[Category: Rodgers, C M.L.]] | [[Category: Rodgers, C M.L.]] | ||
[[Category: Phosphoinositide kinase]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||
Revision as of 00:10, 27 July 2012
Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors.Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors.
Template:ABSTRACT PUBMED 21269826
About this StructureAbout this Structure
3pre is a 1 chain structure of Phosphoinositide 3-Kinases with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Liu KK, Huang X, Bagrodia S, Chen JH, Greasley S, Cheng H, Sun S, Knighton D, Rodgers C, Rafidi K, Zou A, Xiao J, Yan S. Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1270-4. Epub 2010 Dec 10. PMID:21269826 doi:10.1016/j.bmcl.2010.12.026