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| [[Image:3ela.png|left|200px]] | | [[Image:3ela.png|left|200px]] |
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| {{STRUCTURE_3ela| PDB=3ela | SCENE= }} | | {{STRUCTURE_3ela| PDB=3ela | SCENE= }} |
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| ===Crystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factor=== | | ===Crystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factor=== |
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| {{ABSTRACT_PUBMED_18640965}} | | {{ABSTRACT_PUBMED_18640965}} |
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| ==Disease== | | ==About this Structure== |
| Known disease associated with this structure: Factor VII deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]], Myocardial infarction, decreased susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]]
| | [[3ela]] is a 3 chain structure of [[Factor VIIa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ELA OCA]. |
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| ==About this Structure== | | ==See Also== |
| 3ELA is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ELA OCA].
| | *[[Factor VIIa|Factor VIIa]] |
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| ==Reference== | | ==Reference== |
| <ref group="xtra">PMID:18640965</ref><references group="xtra"/> | | <ref group="xtra">PMID:018640965</ref><references group="xtra"/> |
| [[Category: Coagulation factor VIIa]] | | [[Category: Coagulation factor VIIa]] |
| [[Category: Homo sapiens]] | | [[Category: Homo sapiens]] |
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| [[Category: Fodje, M.]] | | [[Category: Fodje, M.]] |
| [[Category: Svensson, L A.]] | | [[Category: Svensson, L A.]] |
| [[Category: Allosteric regulation]]
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| [[Category: Allostery]]
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| [[Category: Alternative splicing]]
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| [[Category: Blood clotting]] | | [[Category: Blood clotting]] |
| [[Category: Blood coagulation]] | | [[Category: Hydrolase-hydrolase inhibitor complex]] |
| [[Category: Calcium]]
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| [[Category: Cleavage on pair of basic residue]]
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| [[Category: Disease mutation]]
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| [[Category: Egf-like domain]]
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| [[Category: Exosite]]
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| [[Category: Gamma-carboxyglutamic acid]]
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| [[Category: Glycoprotein]]
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| [[Category: Hydrolase]]
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| [[Category: Hydroxylation]]
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| [[Category: Lipoprotein]]
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| [[Category: Membrane]]
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| [[Category: Palmitate]]
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| [[Category: Pharmaceutical]]
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| [[Category: Polymorphism]]
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| [[Category: Protease]]
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| [[Category: Secreted]]
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| [[Category: Serine protease]] | | [[Category: Serine protease]] |
| [[Category: Transmembrane]]
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| [[Category: Zymogen]]
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| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:17:26 2009''
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