2wi2: Difference between revisions

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[[Image:2wi2.png|left|200px]]
[[Image:2wi2.png|left|200px]]


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{{STRUCTURE_2wi2|  PDB=2wi2  |  SCENE=  }}  
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===ORALLY ACTIVE 2-AMINO THIENOPYRIMIDINE INHIBITORS OF THE HSP90 CHAPERONE===
===ORALLY ACTIVE 2-AMINO THIENOPYRIMIDINE INHIBITORS OF THE HSP90 CHAPERONE===


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==See Also==
==See Also==
*[[Heat Shock Proteins]]
*[[Heat Shock Proteins|Heat Shock Proteins]]


==Reference==
==Reference==

Revision as of 18:29, 26 July 2012

File:2wi2.png

Template:STRUCTURE 2wi2

ORALLY ACTIVE 2-AMINO THIENOPYRIMIDINE INHIBITORS OF THE HSP90 CHAPERONEORALLY ACTIVE 2-AMINO THIENOPYRIMIDINE INHIBITORS OF THE HSP90 CHAPERONE

Template:ABSTRACT PUBMED 19610616

About this StructureAbout this Structure

2wi2 is a 2 chain structure of Heat Shock Proteins with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Brough PA, Barril X, Borgognoni J, Chene P, Davies NG, Davis B, Drysdale MJ, Dymock B, Eccles SA, Garcia-Echeverria C, Fromont C, Hayes A, Hubbard RE, Jordan AM, Jensen MR, Massey A, Merrett A, Padfield A, Parsons R, Radimerski T, Raynaud FI, Robertson A, Roughley SD, Schoepfer J, Simmonite H, Sharp SY, Surgenor A, Valenti M, Walls S, Webb P, Wood M, Workman P, Wright L. Combining Hit Identification Strategies: Fragment-Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3-d]pyrimidine Inhibitors of the Hsp90 Molecular Chaperone. J Med Chem. 2009 Jul 17. PMID:19610616 doi:10.1021/jm900357y

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