2xby: Difference between revisions
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[[Image:2xby.png|left|200px]] | [[Image:2xby.png|left|200px]] | ||
{{STRUCTURE_2xby| PDB=2xby | SCENE= }} | {{STRUCTURE_2xby| PDB=2xby | SCENE= }} | ||
===FACTOR XA IN COMPLEX WITH A PYRROLIDINE-3,4-DICARBOXYLIC ACID INHIBITOR=== | ===FACTOR XA IN COMPLEX WITH A PYRROLIDINE-3,4-DICARBOXYLIC ACID INHIBITOR=== | ||
{{ABSTRACT_PUBMED_20650636}} | {{ABSTRACT_PUBMED_20650636}} | ||
==About this Structure== | ==About this Structure== | ||
[[2xby]] is a 2 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XBY OCA]. | |||
==See Also== | |||
*[[Factor Xa|Factor Xa]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020650636</ref><references group="xtra"/> | ||
[[Category: Coagulation factor Xa]] | [[Category: Coagulation factor Xa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 16:07, 26 July 2012
FACTOR XA IN COMPLEX WITH A PYRROLIDINE-3,4-DICARBOXYLIC ACID INHIBITORFACTOR XA IN COMPLEX WITH A PYRROLIDINE-3,4-DICARBOXYLIC ACID INHIBITOR
Template:ABSTRACT PUBMED 20650636
About this StructureAbout this Structure
2xby is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Anselm L, Banner DW, Benz J, Zbinden KG, Himber J, Hilpert H, Huber W, Kuhn B, Mary JL, Otteneder MB, Panday N, Ricklin F, Stahl M, Thomi S, Haap W. Discovery of a factor Xa inhibitor (3R,4R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide] 4-[[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide] as a clinical candidate. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5313-9. Epub 2010 Jul 1. PMID:20650636 doi:10.1016/j.bmcl.2010.06.126