1imd: Difference between revisions

Revision as of 16:00, 26 July 2012

Ligands:

,

Gene:

CDNA (Homo sapiens)

Activity:

Inositol-phosphate phosphatase, with EC number 3.1.3.25

Structural annotation:
Resources:	CATH : 1Imda01, 1Imda02, 1Imdb02, 1Imdb01 InterPro : Ipr000760, Ipr000146 Pfam : PF00459 SCOP : d1imda_, d1imdb_ UniProt : P29218

Functional annotation:
Cellular component:	cytoplasm
Biological process:	signal transduction carbohydrate metabolic process phosphate metabolic process phosphatidylinositol biosynthetic process
Molecular function:	inositol-1(or 4)-monophosphatase activity metal ion binding lithium ion binding phosphoric ester hydrolase activity hydrolase activity magnesium ion binding inositol or phosphatidylinositol phosphatase activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

1imd is a 2 chain structure of Inositol Monophosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

↑ Bone R, Frank L, Springer JP, Atack JR. Structural studies of metal binding by inositol monophosphatase: evidence for two-metal ion catalysis. Biochemistry. 1994 Aug 16;33(32):9468-76. PMID:8068621

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