3gpw: Difference between revisions
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[[Image:3gpw.png|left|200px]] | |||
[[Image:3gpw. | |||
{{STRUCTURE_3gpw| PDB=3gpw | SCENE= }} | {{STRUCTURE_3gpw| PDB=3gpw | SCENE= }} | ||
===Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: irreversible inhibitor ligand=== | ===Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: irreversible inhibitor ligand=== | ||
{{ABSTRACT_PUBMED_19678642}} | {{ABSTRACT_PUBMED_19678642}} | ||
==About this Structure== | ==About this Structure== | ||
[[3gpw]] is a 28 chain structure of [[Proteasome]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GPW OCA]. | |||
==See Also== | |||
*[[Proteasome|Proteasome]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019678642</ref><references group="xtra"/> | ||
[[Category: Proteasome endopeptidase complex]] | [[Category: Proteasome endopeptidase complex]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| Line 32: | Line 23: | ||
[[Category: Potts, C B.]] | [[Category: Potts, C B.]] | ||
[[Category: Cancer therapy]] | [[Category: Cancer therapy]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Immunology]] | [[Category: Immunology]] | ||
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[[Category: Time-dependent elimination of a defined leaving group]] | [[Category: Time-dependent elimination of a defined leaving group]] | ||
[[Category: Ubiquitin]] | [[Category: Ubiquitin]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 15:49, 26 July 2012
Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: irreversible inhibitor ligandCrystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: irreversible inhibitor ligand
Template:ABSTRACT PUBMED 19678642
About this StructureAbout this Structure
3gpw is a 28 chain structure of Proteasome with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Groll M, McArthur KA, Macherla VR, Manam RR, Potts BC. Snapshots of the fluorosalinosporamide/20S complex offer mechanistic insights for fine tuning proteasome inhibition. J Med Chem. 2009 Sep 10;52(17):5420-8. PMID:19678642 doi:10.1021/jm900559x
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Pages with broken file links
- Proteasome endopeptidase complex
- Saccharomyces cerevisiae
- Arthur, K A.M.
- Groll, M.
- Macherla, V R.
- Manam, R R.
- Potts, C B.
- Cancer therapy
- Hydrolase
- Immunology
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Protease
- Proteasome
- Threonine protease
- Time-dependent elimination of a defined leaving group
- Ubiquitin
- Zymogen