4agp: Difference between revisions

Revision as of 14:34, 26 July 2012

4agp is a 2 chain structure of P53 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

↑ Wilcken R, Liu X, Zimmermann MO, Rutherford TJ, Fersht AR, Joerger AC, Boeckler FM. Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant p53. J Am Chem Soc. 2012 Apr 18;134(15):6810-8. Epub 2012 Apr 5. PMID:22439615 doi:10.1021/ja301056a
↑ Joerger AC, Ang HC, Fersht AR. Structural basis for understanding oncogenic p53 mutations and designing rescue drugs. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:17015838

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 [[Image:4agp.png|left|200px]]
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 {{STRUCTURE_4agp|  PDB=4agp  |  SCENE=  }}
 ===Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5176===
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 {{ABSTRACT_PUBMED_22439615}}
 ==About this Structure==
-[[4agp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AGP OCA].
+[[4agp]] is a 2 chain structure of [[P53]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AGP OCA].
+==See Also==
+*[[P53|P53]]
 ==Reference==