2opq: Difference between revisions
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[[Image:2opq.png|left|200px]] | [[Image:2opq.png|left|200px]] | ||
{{STRUCTURE_2opq| PDB=2opq | SCENE= }} | {{STRUCTURE_2opq| PDB=2opq | SCENE= }} | ||
===Crystal Structure of L100I Mutant HIV-1 Reverse Transcriptase in Complex with GW420867X.=== | ===Crystal Structure of L100I Mutant HIV-1 Reverse Transcriptase in Complex with GW420867X.=== | ||
{{ABSTRACT_PUBMED_17441703}} | {{ABSTRACT_PUBMED_17441703}} | ||
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==See Also== | ==See Also== | ||
*[[Reverse transcriptase]] | *[[Reverse transcriptase|Reverse transcriptase]] | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:017441703</ref><references group="xtra"/> | ||
[[Category: Hiv-1 m:b_hxb2r]] | [[Category: Hiv-1 m:b_hxb2r]] | ||
[[Category: RNA-directed DNA polymerase]] | [[Category: RNA-directed DNA polymerase]] | ||
Revision as of 14:22, 26 July 2012
Crystal Structure of L100I Mutant HIV-1 Reverse Transcriptase in Complex with GW420867X.Crystal Structure of L100I Mutant HIV-1 Reverse Transcriptase in Complex with GW420867X.
Template:ABSTRACT PUBMED 17441703
About this StructureAbout this Structure
2opq is a 2 chain structure of Reverse transcriptase with sequence from Hiv-1 m:b_hxb2r. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Ren J, Nichols CE, Chamberlain PP, Weaver KL, Short SA, Chan JH, Kleim JP, Stammers DK. Relationship of potency and resilience to drug resistant mutations for GW420867X revealed by crystal structures of inhibitor complexes for wild-type, Leu100Ile, Lys101Glu, and Tyr188Cys mutant HIV-1 reverse transcriptases. J Med Chem. 2007 May 17;50(10):2301-9. Epub 2007 Apr 19. PMID:17441703 doi:http://dx.doi.org/10.1021/jm061117m