2bl2: Difference between revisions
New page: left|200px<br /> <applet load="2bl2" size="450" color="white" frame="true" align="right" spinBox="true" caption="2bl2, resolution 2.10Å" /> '''THE MEMBRANE ROTOR ... |
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==About this Structure== | ==About this Structure== | ||
2BL2 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Enterococcus_hirae Enterococcus hirae]] with NA, LHG and UMQ as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BL2 OCA]]. | 2BL2 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Enterococcus_hirae Enterococcus hirae]] with NA, LHG and UMQ as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/H(+)-transporting_two-sector_ATPase H(+)-transporting two-sector ATPase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14]]. Structure known Active Site: . Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BL2 OCA]]. | ||
==Reference== | ==Reference== | ||
Structure of the rotor of the V-Type Na+-ATPase from Enterococcus hirae., Murata T, Yamato I, Kakinuma Y, Leslie AG, Walker JE, Science. 2005 Apr 29;308(5722):654-9. Epub 2005 Mar 31. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15802565 15802565] | Structure of the rotor of the V-Type Na+-ATPase from Enterococcus hirae., Murata T, Yamato I, Kakinuma Y, Leslie AG, Walker JE, Science. 2005 Apr 29;308(5722):654-9. Epub 2005 Mar 31. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15802565 15802565] | ||
[[Category: Enterococcus hirae]] | [[Category: Enterococcus hirae]] | ||
[[Category: H(+)-transporting two-sector ATPase]] | |||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Kakinuma, Y.]] | [[Category: Kakinuma, Y.]] | ||
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[[Category: v-type atpase]] | [[Category: v-type atpase]] | ||
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Revision as of 14:47, 30 October 2007
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THE MEMBRANE ROTOR OF THE V-TYPE ATPASE FROM ENTEROCOCCUS HIRAE
OverviewOverview
The membrane rotor ring from the vacuolar-type (V-type) sodium ion-pumping, adenosine triphosphatase (Na+-ATPase) from Enterococcus hirae consists of, 10 NtpK subunits, which are homologs of the 16-kilodalton and 8-kilodalton, proteolipids found in other V-ATPases and in F1Fo- or F-ATPases, respectively. Each NtpK subunit has four transmembrane alpha helices, with, a sodium ion bound between helices 2 and 4 at a site buried deeply in the, membrane that includes the essential residue glutamate-139. This site is, probably connected to the membrane surface by two half-channels in subunit, NtpI, against which the ring rotates. Symmetry mismatch between the rotor, and catalytic domains appears to be an intrinsic feature of both V- and, F-ATPases.
About this StructureAbout this Structure
2BL2 is a [Single protein] structure of sequence from [Enterococcus hirae] with NA, LHG and UMQ as [ligands]. Active as [H(+)-transporting two-sector ATPase], with EC number [3.6.3.14]. Structure known Active Site: . Full crystallographic information is available from [OCA].
ReferenceReference
Structure of the rotor of the V-Type Na+-ATPase from Enterococcus hirae., Murata T, Yamato I, Kakinuma Y, Leslie AG, Walker JE, Science. 2005 Apr 29;308(5722):654-9. Epub 2005 Mar 31. PMID:15802565
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