3jwq: Difference between revisions

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[[Image:3jwq.png|left|200px]]
[[Image:3jwq.png|left|200px]]


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{{STRUCTURE_3jwq|  PDB=3jwq  |  SCENE=  }}  
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===Crystal structure of chimeric PDE5/PDE6 catalytic domain complexed with sildenafil===
===Crystal structure of chimeric PDE5/PDE6 catalytic domain complexed with sildenafil===


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{{ABSTRACT_PUBMED_19798052}}


==About this Structure==
==About this Structure==
3JWQ is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JWQ OCA].  
[[3jwq]] is a 4 chain structure of [[Phosphodiesterase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JWQ OCA].  
 
==See Also==
*[[Phosphodiesterase|Phosphodiesterase]]


==Reference==
==Reference==
<ref group="xtra">PMID:19798052</ref><references group="xtra"/>
<ref group="xtra">PMID:019798052</ref><ref group="xtra">PMID:020600113</ref><references group="xtra"/>
[[Category: 3',5'-cyclic-GMP phosphodiesterase]]
[[Category: 3',5'-cyclic-GMP phosphodiesterase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Ramaswamy, S.]]
[[Category: Ramaswamy, S.]]
[[Category: Allosteric enzyme]]
[[Category: Allosteric enzyme]]
[[Category: Alternative splicing]]
[[Category: Cell membrane]]
[[Category: Cell membrane]]
[[Category: Cgmp]]
[[Category: Cgmp]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Prenylation]]
[[Category: Prenylation]]
[[Category: Sensory transduction]]
[[Category: Sensory transduction]]
[[Category: Vision]]
[[Category: Vision]]
[[Category: Zinc]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 21 09:47:39 2009''

Revision as of 11:54, 26 July 2012

File:3jwq.png

Template:STRUCTURE 3jwq

Crystal structure of chimeric PDE5/PDE6 catalytic domain complexed with sildenafilCrystal structure of chimeric PDE5/PDE6 catalytic domain complexed with sildenafil

Template:ABSTRACT PUBMED 19798052

About this StructureAbout this Structure

3jwq is a 4 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1][xtra 2]

  1. Barren B, Gakhar L, Muradov H, Boyd KK, Ramaswamy S, Artemyev NO. Structural basis of phosphodiesterase 6 inhibition by the C-terminal region of the gamma-subunit. EMBO J. 2009 Nov 18;28(22):3613-22. Epub 2009 Oct 1. PMID:19798052 doi:10.1038/emboj.2009.284
  2. Goc A, Chami M, Lodowski DT, Bosshart P, Moiseenkova-Bell V, Baehr W, Engel A, Palczewski K. Structural characterization of the rod cGMP phosphodiesterase 6. J Mol Biol. 2010 Aug 20;401(3):363-73. Epub 2010 Jul 1. PMID:20600113 doi:10.1016/j.jmb.2010.06.044

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