3bef: Difference between revisions

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[[Image:3bef.png|left|200px]]
[[Image:3bef.png|left|200px]]


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{{STRUCTURE_3bef|  PDB=3bef  |  SCENE=  }}  
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===Crystal structure of thrombin bound to the extracellular fragment of PAR1===
===Crystal structure of thrombin bound to the extracellular fragment of PAR1===


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{{ABSTRACT_PUBMED_18250335}}
{{ABSTRACT_PUBMED_18250335}}


==About this Structure==
==About this Structure==
[[3bef]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BEF OCA].  
[[3bef]] is a 6 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BEF OCA].  
 
==See Also==
*[[Thrombin|Thrombin]]


==Reference==
==Reference==
<ref group="xtra">PMID:18250335</ref><ref group="xtra">PMID:15152000</ref><ref group="xtra">PMID:16954215</ref><references group="xtra"/>
<ref group="xtra">PMID:018250335</ref><ref group="xtra">PMID:015152000</ref><ref group="xtra">PMID:016954215</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Acute phase]]
[[Category: Acute phase]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
[[Category: Calcium]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
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[[Category: Membrane]]
[[Category: Membrane]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Receptor]]
[[Category: Receptor]]
[[Category: Secreted]]
[[Category: Secreted]]

Revision as of 11:51, 26 July 2012

File:3bef.png

Template:STRUCTURE 3bef

Crystal structure of thrombin bound to the extracellular fragment of PAR1Crystal structure of thrombin bound to the extracellular fragment of PAR1

Template:ABSTRACT PUBMED 18250335

About this StructureAbout this Structure

3bef is a 6 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1][xtra 2][xtra 3]

  1. ↑ Gandhi PS, Chen Z, Mathews FS, Di Cera E. Structural identification of the pathway of long-range communication in an allosteric enzyme. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1832-7. Epub 2008 Feb 4. PMID:18250335
  2. ↑ Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E. Molecular dissection of Na+ binding to thrombin. J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:15152000 doi:http://dx.doi.org/10.1074/jbc.M401756200
  3. ↑ Pineda AO, Chen ZW, Bah A, Garvey LC, Mathews FS, Di Cera E. Crystal structure of thrombin in a self-inhibited conformation. J Biol Chem. 2006 Oct 27;281(43):32922-8. Epub 2006 Sep 5. PMID:16954215 doi:http://dx.doi.org/10.1074/jbc.M605530200

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