1dep: Difference between revisions
New page: left|200px<br /><applet load="1dep" size="450" color="white" frame="true" align="right" spinBox="true" caption="1dep" /> '''MEMBRANE PROTEIN, NMR, 1 STRUCTURE'''<br /> ... |
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[[Image:1dep.gif|left|200px]]<br /><applet load="1dep" size=" | [[Image:1dep.gif|left|200px]]<br /><applet load="1dep" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1dep" /> | caption="1dep" /> | ||
'''MEMBRANE PROTEIN, NMR, 1 STRUCTURE'''<br /> | '''MEMBRANE PROTEIN, NMR, 1 STRUCTURE'''<br /> | ||
==Overview== | ==Overview== | ||
The C-terminal part of the third intracellular loop of the | The C-terminal part of the third intracellular loop of the beta-adrenoceptor is capable of stimulating adenylate cyclase in the presence of phospholipid vesicles via the stimulatory guanine nucleotide binding protein (Gs) [Palm et al. (1989) FEBS Lett. 254, 89-93]. We have investigated the structure of synthetic peptides corresponding to residues 284-295 of the turkey erythrocyte adrenoceptor in micelles, trifluoroethanol and aqueous solution, by using 2D 1H NMR and CD. In the presence of phospholipid micelles the peptides display a C-terminal alpha-helical region, whereas the N-terminal part was found to be highly flexible. | ||
==About this Structure== | ==About this Structure== | ||
1DEP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo]. Full crystallographic information is available from [http:// | 1DEP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DEP OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Jung, H.]] | [[Category: Jung, H.]] | ||
[[Category: Schnackerz, K | [[Category: Schnackerz, K D.]] | ||
[[Category: beta-adrenoceptor]] | [[Category: beta-adrenoceptor]] | ||
[[Category: membrane protein]] | [[Category: membrane protein]] | ||
[[Category: micelle-bound peptide]] | [[Category: micelle-bound peptide]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:15:55 2008'' | ||
