2va5: Difference between revisions

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{{Seed}}
[[Image:2va5.png|left|200px]]
[[Image:2va5.png|left|200px]]


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{{STRUCTURE_2va5|  PDB=2va5  |  SCENE=  }}  
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===X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH COMPOUND 8C===
===X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH COMPOUND 8C===


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{{ABSTRACT_PUBMED_17985862}}
{{ABSTRACT_PUBMED_17985862}}


==About this Structure==
==About this Structure==
2VA5 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VA5 OCA].  
[[2va5]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VA5 OCA].  
 
==See Also==
*[[Beta secretase|Beta secretase]]


==Reference==
==Reference==
<ref group="xtra">PMID:17985862</ref><references group="xtra"/>
<ref group="xtra">PMID:017985862</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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[[Category: Sylvester, M.]]
[[Category: Sylvester, M.]]
[[Category: Tian, G.]]
[[Category: Tian, G.]]
[[Category: Alternative splicing]]
[[Category: Alzheimer's disease]]
[[Category: Alzheimer's disease]]
[[Category: Aspartic protease]]
[[Category: Aspartic protease]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:26:10 2009''

Revision as of 10:57, 26 July 2012

File:2va5.png

Template:STRUCTURE 2va5

X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH COMPOUND 8CX-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH COMPOUND 8C

Template:ABSTRACT PUBMED 17985862

About this StructureAbout this Structure

2va5 is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Edwards PD, Albert JS, Sylvester M, Aharony D, Andisik D, Callaghan O, Campbell JB, Carr RA, Chessari G, Congreve M, Frederickson M, Folmer RH, Geschwindner S, Koether G, Kolmodin K, Krumrine J, Mauger RC, Murray CW, Olsson LL, Patel S, Spear N, Tian G. Application of fragment-based lead generation to the discovery of novel, cyclic amidine beta-secretase inhibitors with nanomolar potency, cellular activity, and high ligand efficiency. J Med Chem. 2007 Nov 29;50(24):5912-25. Epub 2007 Nov 7. PMID:17985862 doi:http://dx.doi.org/10.1021/jm070829p

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