3bg8: Difference between revisions

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{{Seed}}
[[Image:3bg8.png|left|200px]]
[[Image:3bg8.jpg|left|200px]]


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===Crystal structure of Factor XIa in complex with Clavatadine A===
===Crystal structure of Factor XIa in complex with Clavatadine A===


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==Disease==
==About this Structure==
Known disease associated with this structure: Factor XI deficiency, autosomal dominant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=264900 264900]], Factor XI deficiency, autosomal recessive OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=264900 264900]]
[[3bg8]] is a 1 chain structure of [[Factor XIa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BG8 OCA].


==About this Structure==
==See Also==
3BG8 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BG8 OCA].
*[[Factor XIa|Factor XIa]]


==Reference==
==Reference==
Clavatadine A, a natural product with selective recognition and irreversible inhibition of factor XIa., Buchanan MS, Carroll AR, Wessling D, Jobling M, Avery VM, Davis RA, Feng Y, Xue Y, Oster L, Fex T, Deinum J, Hooper JN, Quinn RJ, J Med Chem. 2008 Jun 26;51(12):3583-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18510371 18510371]
<ref group="xtra">PMID:018510371</ref><references group="xtra"/>
[[Category: Coagulation factor XIa]]
[[Category: Coagulation factor XIa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Oster, L.]]
[[Category: Oster, L.]]
[[Category: Xue, Y.]]
[[Category: Xue, Y.]]
[[Category: Alternative splicing]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
[[Category: Covalent inhibitor]]
[[Category: Covalent inhibitor]]
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[[Category: Heparin-binding]]
[[Category: Heparin-binding]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Polymorphism]]
[[Category: Protease inhibitor]]
[[Category: Protease inhibitor]]
[[Category: Secreted]]
[[Category: Secreted]]
[[Category: Serine protease]]
[[Category: Serine protease]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 15:00:18 2008''

Revision as of 09:31, 26 July 2012

File:3bg8.png

Template:STRUCTURE 3bg8

Crystal structure of Factor XIa in complex with Clavatadine ACrystal structure of Factor XIa in complex with Clavatadine A

Template:ABSTRACT PUBMED 18510371

About this StructureAbout this Structure

3bg8 is a 1 chain structure of Factor XIa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Buchanan MS, Carroll AR, Wessling D, Jobling M, Avery VM, Davis RA, Feng Y, Xue Y, Oster L, Fex T, Deinum J, Hooper JN, Quinn RJ. Clavatadine A, a natural product with selective recognition and irreversible inhibition of factor XIa. J Med Chem. 2008 Jun 26;51(12):3583-7. PMID:18510371 doi:10.1021/jm800314b

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