3l5f: Difference between revisions

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Revision as of 08:14, 26 July 2012

File:3l5f.png

Template:STRUCTURE 3l5f

Structure of BACE Bound to SCH736201Structure of BACE Bound to SCH736201

Template:ABSTRACT PUBMED 20043696

About this StructureAbout this Structure

3l5f is a 2 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Zhu Z, Sun ZY, Ye Y, Voigt J, Strickland C, Smith EM, Cumming J, Wang L, Wong J, Wang YS, Wyss DF, Chen X, Kuvelkar R, Kennedy ME, Favreau L, Parker E, McKittrick BA, Stamford A, Czarniecki M, Greenlee W, Hunter JC. Discovery of Cyclic Acylguanidines as Highly Potent and Selective beta-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I-Inhibitor Design and Validation ( parallel) (1). J Med Chem. 2010 Feb 11;53(3):951-65. PMID:20043696 doi:10.1021/jm901408p

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OCA
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