1gj5: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older editNewer edit →
m Protected "1gj5" [edit=sysop:move=sysop]
No edit summary
Line 1: Line 1:
[[Image:1gj5.png|left|200px]]
[[Image:1gj5.png|left|200px]]


<!--
The line below this paragraph, containing "STRUCTURE_1gj5", creates the "Structure Box" on the page.
You may change the PDB parameter (which sets the PDB file loaded into the applet)
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
or leave the SCENE parameter empty for the default display.
-->
{{STRUCTURE_1gj5|  PDB=1gj5  |  SCENE=  }}  
{{STRUCTURE_1gj5|  PDB=1gj5  |  SCENE=  }}  


===SELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGN===
===SELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGN===


<!--
The line below this paragraph, {{ABSTRACT_PUBMED_11731301}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11731301 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_11731301}}
{{ABSTRACT_PUBMED_11731301}}


==About this Structure==
==About this Structure==
[[1gj5]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GJ5 OCA].  
[[1gj5]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GJ5 OCA].  


==See Also==
==See Also==
*[[Hirudin]]
*[[Hirudin|Hirudin]]
*[[Thrombin|Thrombin]]


==Reference==
==Reference==
<ref group="xtra">PMID:11731301</ref><references group="xtra"/>
<ref group="xtra">PMID:011731301</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
Line 41: Line 31:
[[Category: Blood clotting]]
[[Category: Blood clotting]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Hydrolase-inhibitor complex]]
[[Category: Oxyanion hole water]]
[[Category: Oxyanion hole water]]
[[Category: Shift of pka of his57]]
[[Category: Shift of pka of his57]]

Revision as of 07:46, 26 July 2012

File:1gj5.png

Template:STRUCTURE 1gj5

SELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGNSELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGN

Template:ABSTRACT PUBMED 11731301

About this StructureAbout this Structure

1gj5 is a 3 chain structure of Hirudin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Katz BA, Sprengeler PA, Luong C, Verner E, Elrod K, Kirtley M, Janc J, Spencer JR, Breitenbucher JG, Hui H, McGee D, Allen D, Martelli A, Mackman RL. Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets. Chem Biol. 2001 Nov;8(11):1107-21. PMID:11731301

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=1gj5&oldid=1453005"