3b3n: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:3b3n.png|left|200px]] | [[Image:3b3n.png|left|200px]] | ||
{{STRUCTURE_3b3n| PDB=3b3n | SCENE= }} | {{STRUCTURE_3b3n| PDB=3b3n | SCENE= }} | ||
===Structure of neuronal NOS heme domain in complex with a inhibitor (+-)-N1-{cis-4'-[(6"-aminopyridin-2"-yl)methyl]pyrrolidin-3'-yl}ethane-1,2-diamine=== | ===Structure of neuronal NOS heme domain in complex with a inhibitor (+-)-N1-{cis-4'-[(6"-aminopyridin-2"-yl)methyl]pyrrolidin-3'-yl}ethane-1,2-diamine=== | ||
{{ABSTRACT_PUBMED_18321097}} | {{ABSTRACT_PUBMED_18321097}} | ||
==About this Structure== | ==About this Structure== | ||
[[3b3n]] is a 2 chain structure of [[Nitric Oxide Synthase]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B3N OCA]. | |||
==See Also== | |||
*[[Nitric Oxide Synthase|Nitric Oxide Synthase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:018321097</ref><references group="xtra"/> | ||
[[Category: Nitric-oxide synthase]] | [[Category: Nitric-oxide synthase]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| Line 29: | Line 20: | ||
[[Category: Li, H.]] | [[Category: Li, H.]] | ||
[[Category: Poulos, T L.]] | [[Category: Poulos, T L.]] | ||
[[Category: Calmodulin-binding]] | [[Category: Calmodulin-binding]] | ||
[[Category: Cell projection]] | [[Category: Cell projection]] | ||
| Line 42: | Line 32: | ||
[[Category: Nitric oxide synthase]] | [[Category: Nitric oxide synthase]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
Revision as of 04:21, 26 July 2012
Structure of neuronal NOS heme domain in complex with a inhibitor (+-)-N1-{cis-4'-[(6"-aminopyridin-2"-yl)methyl]pyrrolidin-3'-yl}ethane-1,2-diamine
Template:ABSTRACT PUBMED 18321097
About this StructureAbout this Structure
3b3n is a 2 chain structure of Nitric Oxide Synthase with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Ji H, Stanton BZ, Igarashi J, Li H, Martasek P, Roman LJ, Poulos TL, Silverman RB. Minimal pharmacophoric elements and fragment hopping, an approach directed at molecular diversity and isozyme selectivity. Design of selective neuronal nitric oxide synthase inhibitors. J Am Chem Soc. 2008 Mar 26;130(12):3900-14. Epub 2008 Mar 6. PMID:18321097 doi:10.1021/ja0772041