1rwx: Difference between revisions
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[[Image:1rwx.png|left|200px]] | [[Image:1rwx.png|left|200px]] | ||
{{STRUCTURE_1rwx| PDB=1rwx | SCENE= }} | {{STRUCTURE_1rwx| PDB=1rwx | SCENE= }} | ||
===Crystal structure of human caspase-1 in complex with 4-oxo-3-{6-[4-(quinoxalin-2-yloxy)-benzoylamino]-2-thiophen-2-yl-hexanoylamino}-butyric acid=== | ===Crystal structure of human caspase-1 in complex with 4-oxo-3-{6-[4-(quinoxalin-2-yloxy)-benzoylamino]-2-thiophen-2-yl-hexanoylamino}-butyric acid=== | ||
{{ABSTRACT_PUBMED_16274992}} | {{ABSTRACT_PUBMED_16274992}} | ||
==About this Structure== | ==About this Structure== | ||
[[1rwx]] is a 2 chain structure of [[Caspase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RWX OCA]. | |||
==See Also== | |||
*[[Caspase|Caspase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:016274992</ref><references group="xtra"/> | ||
[[Category: Caspase-1]] | [[Category: Caspase-1]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Protein-small molecule inhibitor complex]] | [[Category: Protein-small molecule inhibitor complex]] | ||
Revision as of 04:02, 26 July 2012
Crystal structure of human caspase-1 in complex with 4-oxo-3-{6-[4-(quinoxalin-2-yloxy)-benzoylamino]-2-thiophen-2-yl-hexanoylamino}-butyric acidCrystal structure of human caspase-1 in complex with 4-oxo-3-{6-[4-(quinoxalin-2-yloxy)-benzoylamino]-2-thiophen-2-yl-hexanoylamino}-butyric acid
Template:ABSTRACT PUBMED 16274992
About this StructureAbout this Structure
1rwx is a 2 chain structure of Caspase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Fahr BT, O'Brien T, Pham P, Waal ND, Baskaran S, Raimundo BC, Lam JW, Sopko MM, Purkey HE, Romanowski MJ. Tethering identifies fragment that yields potent inhibitors of human caspase-1. Bioorg Med Chem Lett. 2006 Feb;16(3):559-62. Epub 2005 Nov 4. PMID:16274992 doi:10.1016/j.bmcl.2005.10.048