3dds: Difference between revisions
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[[Image:3dds.png|left|200px]] | [[Image:3dds.png|left|200px]] | ||
{{STRUCTURE_3dds| PDB=3dds | SCENE= }} | {{STRUCTURE_3dds| PDB=3dds | SCENE= }} | ||
===Crystal structure of glycogen phosphorylase complexed with an anthranilimide based inhibitor GSK261=== | ===Crystal structure of glycogen phosphorylase complexed with an anthranilimide based inhibitor GSK261=== | ||
{{ABSTRACT_PUBMED_19138846}} | {{ABSTRACT_PUBMED_19138846}} | ||
==About this Structure== | ==About this Structure== | ||
[[3dds]] is a 2 chain structure of [[Glycogen Phosphorylase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DDS OCA]. | |||
==See Also== | |||
*[[Glycogen Phosphorylase|Glycogen Phosphorylase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019138846</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Phosphorylase]] | [[Category: Phosphorylase]] | ||
[[Category: Nolte, R T.]] | [[Category: Nolte, R T.]] | ||
[[Category: Allosteric enzyme]] | [[Category: Allosteric enzyme]] | ||
[[Category: Carbohydrate metabolism]] | [[Category: Carbohydrate metabolism]] | ||
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[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Pyridoxal phosphate]] | [[Category: Pyridoxal phosphate]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 03:01, 26 July 2012
Crystal structure of glycogen phosphorylase complexed with an anthranilimide based inhibitor GSK261Crystal structure of glycogen phosphorylase complexed with an anthranilimide based inhibitor GSK261
Template:ABSTRACT PUBMED 19138846
About this StructureAbout this Structure
3dds is a 2 chain structure of Glycogen Phosphorylase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Thomson SA, Banker P, Bickett DM, Boucheron JA, Carter HL, Clancy DC, Cooper JP, Dickerson SH, Garrido DM, Nolte RT, Peat AJ, Sheckler LR, Sparks SM, Tavares FX, Wang L, Wang TY, Weiel JE. Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1177-82. Epub 2008 Dec 25. PMID:19138846 doi:10.1016/j.bmcl.2008.12.085