1ym4: Difference between revisions

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[[Image:1ym4.png|left|200px]]
[[Image:1ym4.png|left|200px]]


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===Crystal structure of human beta secretase complexed with NVP-AMK640===
===Crystal structure of human beta secretase complexed with NVP-AMK640===


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==About this Structure==
==About this Structure==
1YM4 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YM4 OCA].  
[[1ym4]] is a 6 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YM4 OCA].  
 
==See Also==
*[[Beta secretase|Beta secretase]]


==Reference==
==Reference==
<ref group="xtra">PMID:16078837</ref><references group="xtra"/>
<ref group="xtra">PMID:016078837</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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[[Category: Aspartic protease]]
[[Category: Aspartic protease]]
[[Category: Beta-secretase]]
[[Category: Beta-secretase]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Memapsin2]]
[[Category: Memapsin2]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:53:11 2009''

Revision as of 02:36, 26 July 2012

File:1ym4.png

Template:STRUCTURE 1ym4

Crystal structure of human beta secretase complexed with NVP-AMK640Crystal structure of human beta secretase complexed with NVP-AMK640

Template:ABSTRACT PUBMED 16078837

About this StructureAbout this Structure

1ym4 is a 6 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Hanessian S, Yun H, Hou Y, Yang G, Bayrakdarian M, Therrien E, Moitessier N, Roggo S, Veenstra S, Tintelnot-Blomley M, Rondeau JM, Ostermeier C, Strauss A, Ramage P, Paganetti P, Neumann U, Betschart C. Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics. J Med Chem. 2005 Aug 11;48(16):5175-90. PMID:16078837 doi:10.1021/jm050142+

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