2i40: Difference between revisions

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[[Image:2i40.png|left|200px]]
[[Image:2i40.png|left|200px]]


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{{STRUCTURE_2i40|  PDB=2i40  |  SCENE=  }}  
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===Cdk2/Cyclin A complexed with a thiophene carboxamide inhibitor===
===Cdk2/Cyclin A complexed with a thiophene carboxamide inhibitor===


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{{ABSTRACT_PUBMED_16997559}}
{{ABSTRACT_PUBMED_16997559}}


==About this Structure==
==About this Structure==
2I40 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I40 OCA].  
[[2i40]] is a 4 chain structure of [[Cell Division Protein Kinase 2]] and [[Cyclin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I40 OCA].  
 
==See Also==
*[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]]
*[[Cyclin|Cyclin]]


==Reference==
==Reference==
<ref group="xtra">PMID:16997559</ref><references group="xtra"/>
<ref group="xtra">PMID:016997559</ref><references group="xtra"/>
[[Category: Cyclin-dependent kinase]]
[[Category: Cyclin-dependent kinase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Cyclin]]
[[Category: Cyclin]]
[[Category: Kinase]]
[[Category: Kinase]]
 
[[Category: Transferase-cell cycle complex]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:41:37 2009''

Revision as of 02:20, 26 July 2012

File:2i40.png

Template:STRUCTURE 2i40

Cdk2/Cyclin A complexed with a thiophene carboxamide inhibitorCdk2/Cyclin A complexed with a thiophene carboxamide inhibitor

Template:ABSTRACT PUBMED 16997559

About this StructureAbout this Structure

2i40 is a 4 chain structure of Cell Division Protein Kinase 2 and Cyclin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Bamborough P, Christopher JA, Cutler GJ, Dickson MC, Mellor GW, Morey JV, Patel CB, Shewchuk LM. 5-(1H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-epsilon kinase. Bioorg Med Chem Lett. 2006 Dec 15;16(24):6236-40. Epub 2006 Sep 25. PMID:16997559 doi:10.1016/j.bmcl.2006.09.018

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