2wcx: Difference between revisions

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[[Image:2wcx.png|left|200px]]
[[Image:2wcx.png|left|200px]]


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{{STRUCTURE_2wcx|  PDB=2wcx  |  SCENE=  }}  
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===CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN COMPLEX WITH THIENOPYRROLE-BASED FINGER-LOOP INHIBITORS===
===CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN COMPLEX WITH THIENOPYRROLE-BASED FINGER-LOOP INHIBITORS===


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==See Also==
==See Also==
*[[RNA polymerase]]
*[[RNA polymerase|RNA polymerase]]


==Reference==
==Reference==

Revision as of 01:17, 26 July 2012

File:2wcx.png

Template:STRUCTURE 2wcx

CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN COMPLEX WITH THIENOPYRROLE-BASED FINGER-LOOP INHIBITORSCRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN COMPLEX WITH THIENOPYRROLE-BASED FINGER-LOOP INHIBITORS

Template:ABSTRACT PUBMED 19672916

About this StructureAbout this Structure

2wcx is a 1 chain structure of RNA polymerase with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1][xtra 2]

  1. ↑ Martin Hernando JI, Ontoria JM, Malancona S, Attenni B, Fiore F, Bonelli F, Koch U, Di Marco S, Colarusso S, Ponzi S, Gennari N, Vignetti SE, Rico Ferreira MD, Habermann J, Rowley M, Narjes F. Optimization of Thienopyrrole-Based Finger-Loop Inhibitors of the Hepatitis C Virus NS5B Polymerase. ChemMedChem. 2009 Aug 11. PMID:19672916 doi:10.1002/cmdc.200900184
  2. ↑ Di Marco S, Volpari C, Tomei L, Altamura S, Harper S, Narjes F, Koch U, Rowley M, De Francesco R, Migliaccio G, Carfi A. Interdomain communication in hepatitis C virus polymerase abolished by small molecule inhibitors bound to a novel allosteric site. J Biol Chem. 2005 Aug 19;280(33):29765-70. Epub 2005 Jun 13. PMID:15955819 doi:http://dx.doi.org/10.1074/jbc.M505423200

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