3srq: Difference between revisions
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[[Image:3srq.png|left|200px]] | [[Image:3srq.png|left|200px]] | ||
{{STRUCTURE_3srq| PDB=3srq | SCENE= }} | {{STRUCTURE_3srq| PDB=3srq | SCENE= }} | ||
===S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines=== | ===S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines=== | ||
{{ABSTRACT_PUBMED_21831637}} | {{ABSTRACT_PUBMED_21831637}} | ||
==About this Structure== | ==About this Structure== | ||
[[3srq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SRQ OCA]. | [[3srq]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SRQ OCA]. | ||
==See Also== | |||
*[[Dihydrofolate reductase|Dihydrofolate reductase]] | |||
==Reference== | ==Reference== |
Revision as of 21:18, 25 July 2012
S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolinesS. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines
Template:ABSTRACT PUBMED 21831637
About this StructureAbout this Structure
3srq is a 1 chain structure of Dihydrofolate reductase with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Li X, Hilgers M, Cunningham M, Chen Z, Trzoss M, Zhang J, Kohnen L, Lam T, Creighton C, Gc K, Nelson K, Kwan B, Stidham M, Brown-Driver V, Shaw KJ, Finn J. Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5171-6. Epub 2011 Jul 23. PMID:21831637 doi:10.1016/j.bmcl.2011.07.059