2v0t: Difference between revisions
Jump to navigation
Jump to search
m Protected "2v0t" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:2v0t.png|left|200px]] | [[Image:2v0t.png|left|200px]] | ||
{{STRUCTURE_2v0t| PDB=2v0t | SCENE= }} | {{STRUCTURE_2v0t| PDB=2v0t | SCENE= }} | ||
===THE A178L MUTATION IN THE C-TERMINAL HINGE OF THE FLEXIBLE LOOP-6 OF TRIOSEPHOSPHATE ISOMERASE (TIM) INDUCES A MORE CLOSED CONFORMATION OF THIS HINGE REGION IN DIMERIC AND MONOMERIC TIM=== | ===THE A178L MUTATION IN THE C-TERMINAL HINGE OF THE FLEXIBLE LOOP-6 OF TRIOSEPHOSPHATE ISOMERASE (TIM) INDUCES A MORE CLOSED CONFORMATION OF THIS HINGE REGION IN DIMERIC AND MONOMERIC TIM=== | ||
{{ABSTRACT_PUBMED_18219118}} | {{ABSTRACT_PUBMED_18219118}} | ||
==About this Structure== | ==About this Structure== | ||
[[2v0t]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V0T OCA]. | [[2v0t]] is a 8 chain structure of [[TIM test]] and [[Triose Phosphate Isomerase]] with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V0T OCA]. | ||
==See Also== | |||
*[[TIM test|TIM test]] | |||
*[[Triose Phosphate Isomerase|Triose Phosphate Isomerase]] | |||
==Reference== | ==Reference== | ||
Revision as of 20:59, 25 July 2012
THE A178L MUTATION IN THE C-TERMINAL HINGE OF THE FLEXIBLE LOOP-6 OF TRIOSEPHOSPHATE ISOMERASE (TIM) INDUCES A MORE CLOSED CONFORMATION OF THIS HINGE REGION IN DIMERIC AND MONOMERIC TIMTHE A178L MUTATION IN THE C-TERMINAL HINGE OF THE FLEXIBLE LOOP-6 OF TRIOSEPHOSPHATE ISOMERASE (TIM) INDUCES A MORE CLOSED CONFORMATION OF THIS HINGE REGION IN DIMERIC AND MONOMERIC TIM
Template:ABSTRACT PUBMED 18219118
About this StructureAbout this Structure
2v0t is a 8 chain structure of TIM test and Triose Phosphate Isomerase with sequence from Trypanosoma brucei brucei. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Alahuhta M, Casteleijn MG, Neubauer P, Wierenga RK. Structural studies show that the A178L mutation in the C-terminal hinge of the catalytic loop-6 of triosephosphate isomerase (TIM) induces a closed-like conformation in dimeric and monomeric TIM. Acta Crystallogr D Biol Crystallogr. 2008 Feb;64(Pt 2):178-88. Epub 2008, Jan 16. PMID:18219118 doi:10.1107/S0907444907059021