2zb0: Difference between revisions
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[[Image:2zb0.png|left|200px]] | [[Image:2zb0.png|left|200px]] | ||
{{STRUCTURE_2zb0| PDB=2zb0 | SCENE= }} | {{STRUCTURE_2zb0| PDB=2zb0 | SCENE= }} | ||
===Crystal structure of P38 in complex with biphenyl amide inhibitor=== | ===Crystal structure of P38 in complex with biphenyl amide inhibitor=== | ||
{{ABSTRACT_PUBMED_18006306}} | {{ABSTRACT_PUBMED_18006306}} | ||
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==See Also== | ==See Also== | ||
*[[Mitogen-activated protein kinase]] | *[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]] | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:018006306</ref><ref group="xtra">PMID:017981461</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mitogen-activated protein kinase]] | [[Category: Mitogen-activated protein kinase]] | ||
[[Category: Somers, D O.]] | [[Category: Somers, D O.]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Map kinase]] | [[Category: Map kinase]] | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
Revision as of 20:08, 25 July 2012
Crystal structure of P38 in complex with biphenyl amide inhibitorCrystal structure of P38 in complex with biphenyl amide inhibitor
Template:ABSTRACT PUBMED 18006306
About this StructureAbout this Structure
2zb0 is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Angell RM, Bamborough P, Cleasby A, Cockerill SG, Jones KL, Mooney CJ, Somers DO, Walker AL. Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode. Bioorg Med Chem Lett. 2008 Jan 1;18(1):318-23. Epub 2007 Nov 19. PMID:18006306 doi:10.1016/j.bmcl.2007.10.076
- ↑ Angell RM, Angell TD, Bamborough P, Brown D, Brown M, Buckton JB, Cockerill SG, Edwards CD, Jones KL, Longstaff T, Smee PA, Smith KJ, Somers DO, Walker AL, Willson M. Biphenyl amide p38 kinase inhibitors 2: Optimisation and SAR. Bioorg Med Chem Lett. 2008 Jan 1;18(1):324-8. Epub 2007 Oct 17. PMID:17981461 doi:10.1016/j.bmcl.2007.10.043