3be2: Difference between revisions

Revision as of 18:12, 25 July 2012

3be2 is a 1 chain structure of Vascular Endothelial Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

↑ Harmange JC, Weiss MM, Germain J, Polverino AJ, Borg G, Bready J, Chen D, Choquette D, Coxon A, Demelfi T, Dipietro L, Doerr N, Estrada J, Flynn J, Graceffa RF, Harriman SP, Kaufman S, La DS, Long A, Martin MW, Neervannan S, Patel VF, Potashman M, Regal K, Roveto PM, Schrag ML, Starnes C, Tasker A, Teffera Y, Wang L, White RD, Whittington DA, Zanon R. Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation. J Med Chem. 2008 Mar 27;51(6):1649-67. Epub 2008 Mar 7. PMID:18324761 doi:10.1021/jm701097z

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 [[Image:3be2.png|left|200px]]
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 ===Crystal structure of the VEGFR2 kinase domain in complex with a benzamide inhibitor===
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