3gxu: Difference between revisions

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[[Image:3gxu.png|left|200px]]
[[Image:3gxu.png|left|200px]]


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{{STRUCTURE_3gxu|  PDB=3gxu  |  SCENE=  }}  
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===Crystal structure of Eph receptor and ephrin complex===
===Crystal structure of Eph receptor and ephrin complex===


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{{ABSTRACT_PUBMED_19875447}}
{{ABSTRACT_PUBMED_19875447}}


==About this Structure==
==About this Structure==
[[3gxu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GXU OCA].  
[[3gxu]] is a 2 chain structure of [[Ephrin receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GXU OCA].  
 
==See Also==
*[[Ephrin receptor|Ephrin receptor]]


==Reference==
==Reference==
<ref group="xtra">PMID:19875447</ref><ref group="xtra">PMID:18708347</ref><ref group="xtra">PMID:11780069</ref><references group="xtra"/>
<ref group="xtra">PMID:019875447</ref><ref group="xtra">PMID:018708347</ref><ref group="xtra">PMID:011780069</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Receptor]]
[[Category: Receptor]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]

Revision as of 17:56, 25 July 2012

File:3gxu.png

Template:STRUCTURE 3gxu

Crystal structure of Eph receptor and ephrin complexCrystal structure of Eph receptor and ephrin complex

Template:ABSTRACT PUBMED 19875447

About this StructureAbout this Structure

3gxu is a 2 chain structure of Ephrin receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1][xtra 2][xtra 3]

  1. Qin H, Noberini R, Huan X, Shi J, Pasquale EB, Song J. Structural characterization of the EphA4-Ephrin-B2 complex reveals new features enabling Eph-ephrin binding promiscuity. J Biol Chem. 2010 Jan 1;285(1):644-54. Epub 2009 Oct 29. PMID:19875447 doi:10.1074/jbc.M109.064824
  2. Qin H, Shi J, Noberini R, Pasquale EB, Song J. Crystal structure and NMR binding reveal that two small molecule antagonists target the high affinity ephrin-binding channel of the EphA4 receptor. J Biol Chem. 2008 Oct 24;283(43):29473-84. Epub 2008 Aug 14. PMID:18708347 doi:10.1074/jbc.M804114200
  3. Himanen JP, Rajashankar KR, Lackmann M, Cowan CA, Henkemeyer M, Nikolov DB. Crystal structure of an Eph receptor-ephrin complex. Nature. 2001 Dec 20-27;414(6866):933-8. PMID:11780069 doi:10.1038/414933a

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