3b2v: Difference between revisions

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[[Image:3b2v.png|left|200px]]
[[Image:3b2v.png|left|200px]]


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{{STRUCTURE_3b2v|  PDB=3b2v  |  SCENE=  }}  
{{STRUCTURE_3b2v|  PDB=3b2v  |  SCENE=  }}  


===Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8===
===Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8===


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{{ABSTRACT_PUBMED_18275813}}
{{ABSTRACT_PUBMED_18275813}}


==About this Structure==
==About this Structure==
[[3b2v]] is a 3 chain structure of [[Epidermal Growth Factor Receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B2V OCA].  
[[3b2v]] is a 3 chain structure of [[Antibody]] and [[Epidermal Growth Factor Receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B2V OCA].  


==See Also==
==See Also==
*[[Epidermal Growth Factor Receptor]]
*[[Antibody|Antibody]]
*[[Epidermal Growth Factor Receptor|Epidermal Growth Factor Receptor]]


==Reference==
==Reference==
<ref group="xtra">PMID:18275813</ref><references group="xtra"/>
<ref group="xtra">PMID:018275813</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Kussie, P.]]
[[Category: Kussie, P.]]
[[Category: Li, S.]]
[[Category: Li, S.]]
[[Category: Alternative splicing]]
[[Category: Anti-oncogene]]
[[Category: Anti-oncogene]]
[[Category: Antigen:antibody complex]]
[[Category: Antigen:antibody complex]]
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[[Category: Fab fragment]]
[[Category: Fab fragment]]
[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
[[Category: Immune system/transferase complex]]
[[Category: Immune system-transferase complex]]
[[Category: Kinase]]
[[Category: Kinase]]
[[Category: Membrane]]
[[Category: Membrane]]
[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Secreted]]
[[Category: Secreted]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
[[Category: Ubl conjugation]]

Revision as of 17:48, 25 July 2012

File:3b2v.png

Template:STRUCTURE 3b2v

Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8

Template:ABSTRACT PUBMED 18275813

About this StructureAbout this Structure

3b2v is a 3 chain structure of Antibody and Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Li S, Kussie P, Ferguson KM. Structural basis for EGF receptor inhibition by the therapeutic antibody IMC-11F8. Structure. 2008 Feb;16(2):216-27. PMID:18275813 doi:10.1016/j.str.2007.11.009

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