2b5t: Difference between revisions

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{{Seed}}
[[Image:2b5t.png|left|200px]]
[[Image:2b5t.png|left|200px]]


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===2.1 Angstrom structure of a nonproductive complex between antithrombin, synthetic heparin mimetic SR123781 and two S195A thrombin molecules===
===2.1 Angstrom structure of a nonproductive complex between antithrombin, synthetic heparin mimetic SR123781 and two S195A thrombin molecules===


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{{ABSTRACT_PUBMED_16973611}}
{{ABSTRACT_PUBMED_16973611}}


==Disease==
==About this Structure==
Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]]
[[2b5t]] is a 5 chain structure of [[Antithrombin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5T OCA].


==About this Structure==
==See Also==
2B5T is a 5 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5T OCA].
*[[Antithrombin|Antithrombin]]
*[[Thrombin|Thrombin]]


==Reference==
==Reference==
<ref group="xtra">PMID:16973611</ref><references group="xtra"/>
<ref group="xtra">PMID:016973611</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Blood clotting]]
[[Category: Blood clotting]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 17 09:03:40 2010''

Revision as of 17:27, 25 July 2012

File:2b5t.png

Template:STRUCTURE 2b5t

2.1 Angstrom structure of a nonproductive complex between antithrombin, synthetic heparin mimetic SR123781 and two S195A thrombin molecules2.1 Angstrom structure of a nonproductive complex between antithrombin, synthetic heparin mimetic SR123781 and two S195A thrombin molecules

Template:ABSTRACT PUBMED 16973611

About this StructureAbout this Structure

2b5t is a 5 chain structure of Antithrombin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Johnson DJ, Langdown J, Li W, Luis SA, Baglin TP, Huntington JA. Crystal structure of monomeric native antithrombin reveals a novel reactive center loop conformation. J Biol Chem. 2006 Nov 17;281(46):35478-86. Epub 2006 Sep 13. PMID:16973611 doi:10.1074/jbc.M607204200

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