2eb3: Difference between revisions

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[[Image:2eb3.png|left|200px]]
[[Image:2eb3.png|left|200px]]


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{{STRUCTURE_2eb3|  PDB=2eb3  |  SCENE=  }}  
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===Crystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNP===
===Crystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNP===


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{{ABSTRACT_PUBMED_22349823}}
{{ABSTRACT_PUBMED_22349823}}


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==See Also==
==See Also==
*[[Epidermal Growth Factor Receptor]]
*[[Epidermal Growth Factor Receptor|Epidermal Growth Factor Receptor]]


==Reference==
==Reference==

Revision as of 16:39, 25 July 2012

File:2eb3.png

Template:STRUCTURE 2eb3

Crystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNPCrystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNP

Template:ABSTRACT PUBMED 22349823

About this StructureAbout this Structure

2eb3 is a 1 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Yoshikawa S, Kukimoto-Niino M, Parker L, Handa N, Terada T, Fujimoto T, Terazawa Y, Wakiyama M, Sato M, Sano S, Kobayashi T, Tanaka T, Chen L, Liu ZJ, Wang BC, Shirouzu M, Kawa S, Semba K, Yamamoto T, Yokoyama S. Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor. Oncogene. 2012 Feb 20. doi: 10.1038/onc.2012.21. PMID:22349823 doi:10.1038/onc.2012.21

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