2qe5: Difference between revisions
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[[Image:2qe5.png|left|200px]] | [[Image:2qe5.png|left|200px]] | ||
{{STRUCTURE_2qe5| PDB=2qe5 | SCENE= }} | {{STRUCTURE_2qe5| PDB=2qe5 | SCENE= }} | ||
===Structure of HCV NS5B Bound to an Anthranilic Acid Inhibitor=== | ===Structure of HCV NS5B Bound to an Anthranilic Acid Inhibitor=== | ||
{{ABSTRACT_PUBMED_17402724}} | {{ABSTRACT_PUBMED_17402724}} | ||
==About this Structure== | ==About this Structure== | ||
[[2qe5]] is a 4 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1b Hepatitis c virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QE5 OCA]. | |||
==See Also== | |||
*[[RNA polymerase|RNA polymerase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:017402724</ref><references group="xtra"/> | ||
[[Category: Hepatitis c virus subtype 1b]] | [[Category: Hepatitis c virus subtype 1b]] | ||
[[Category: RNA-directed RNA polymerase]] | [[Category: RNA-directed RNA polymerase]] | ||
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[[Category: Chopra, R.]] | [[Category: Chopra, R.]] | ||
[[Category: Svenson, K.]] | [[Category: Svenson, K.]] | ||
[[Category: Transferase]] | |||
[[Category: Transferase polymerase]] | [[Category: Transferase polymerase]] | ||
Revision as of 14:51, 25 July 2012
Structure of HCV NS5B Bound to an Anthranilic Acid InhibitorStructure of HCV NS5B Bound to an Anthranilic Acid Inhibitor
Template:ABSTRACT PUBMED 17402724
About this StructureAbout this Structure
2qe5 is a 4 chain structure of RNA polymerase with sequence from Hepatitis c virus subtype 1b. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Nittoli T, Curran K, Insaf S, DiGrandi M, Orlowski M, Chopra R, Agarwal A, Howe AY, Prashad A, Floyd MB, Johnson B, Sutherland A, Wheless K, Feld B, O'Connell J, Mansour TS, Bloom J. Identification of anthranilic acid derivatives as a novel class of allosteric inhibitors of hepatitis C NS5B polymerase. J Med Chem. 2007 May 3;50(9):2108-16. Epub 2007 Apr 3. PMID:17402724 doi:10.1021/jm061428x