1ala: Difference between revisions

Revision as of 12:45, 21 February 2008

STRUCTURE OF CHICKEN ANNEXIN V AT 2.25-ANGSTROMS RESOLUTION

OverviewOverview

The crystal structure of chicken annexin V has been solved by molecular replacement and refined at 2.25 A. The final R factor is 19.7% with good geometry. The chicken annexin V structure is very similar to the human annexin V structure, with four similar domains each containing five helices. The structure includes three calcium ions in domains I, II, and IV, each bound by the characteristic K-G-X-G-T-(38 residues)-D/E motif. In view of the structural similarity between human and chicken annexin V, we suggest that they have a common vital function which developed early in evolutionary history.

About this StructureAbout this Structure

1ALA is a Single protein structure of sequence from Gallus gallus with as ligand. Full crystallographic information is available from OCA.

ReferenceReference

Structure of chicken annexin V at 2.25-A resolution., Bewley MC, Boustead CM, Walker JH, Waller DA, Huber R, Biochemistry. 1993 Apr 20;32(15):3923-9. PMID:8471604

Page seeded by OCA on Thu Feb 21 11:45:49 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-[[Image:1ala.jpg|left|200px]]<br /><applet load="1ala" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1ala.jpg|left|200px]]<br /><applet load="1ala" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1ala, resolution 2.25&Aring;" />
 '''STRUCTURE OF CHICKEN ANNEXIN V AT 2.25-ANGSTROMS RESOLUTION'''<br />
 ==Overview==
-The crystal structure of chicken annexin V has been solved by molecular, replacement and refined at 2.25 A. The final R factor is 19.7% with good, geometry. The chicken annexin V structure is very similar to the human, annexin V structure, with four similar domains each containing five, helices. The structure includes three calcium ions in domains I, II, and, IV, each bound by the characteristic K-G-X-G-T-(38 residues)-D/E motif. In, view of the structural similarity between human and chicken annexin V, we, suggest that they have a common vital function which developed early in, evolutionary history.
+The crystal structure of chicken annexin V has been solved by molecular replacement and refined at 2.25 A. The final R factor is 19.7% with good geometry. The chicken annexin V structure is very similar to the human annexin V structure, with four similar domains each containing five helices. The structure includes three calcium ions in domains I, II, and IV, each bound by the characteristic K-G-X-G-T-(38 residues)-D/E motif. In view of the structural similarity between human and chicken annexin V, we suggest that they have a common vital function which developed early in evolutionary history.
 ==About this Structure==
-ALA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] with CA as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1ALA OCA].
+ALA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] with <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ALA OCA].
 ==Reference==
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 [[Category: Gallus gallus]]
 [[Category: Single protein]]
-[[Category: Bewley, M.C.]]
+[[Category: Bewley, M C.]]
 [[Category: Huber, R.]]
-[[Category: Waller, D.A.]]
+[[Category: Waller, D A.]]
 [[Category: CA]]
 [[Category: calcium/phospholipid-binding protein]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 10:56:32 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:45:49 2008''