1klj: Difference between revisions
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[[Image:1klj.png|left|200px]] | [[Image:1klj.png|left|200px]] | ||
{{STRUCTURE_1klj| PDB=1klj | SCENE= }} | {{STRUCTURE_1klj| PDB=1klj | SCENE= }} | ||
===Crystal structure of uninhibited factor VIIa=== | ===Crystal structure of uninhibited factor VIIa=== | ||
{{ABSTRACT_PUBMED_12225752}} | {{ABSTRACT_PUBMED_12225752}} | ||
==About this Structure== | ==About this Structure== | ||
[[1klj]] is a 2 chain structure of [[Factor VIIa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KLJ OCA]. | |||
==See Also== | |||
*[[Factor VIIa|Factor VIIa]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:012225752</ref><ref group="xtra">PMID:011676542</ref><references group="xtra"/> | ||
[[Category: Coagulation factor VIIa]] | [[Category: Coagulation factor VIIa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
Line 36: | Line 27: | ||
[[Category: Sichler, K.]] | [[Category: Sichler, K.]] | ||
[[Category: Extrinsic coagulation pathway]] | [[Category: Extrinsic coagulation pathway]] | ||
[[Category: Hydrolase]] | |||
[[Category: Rational drug design]] | [[Category: Rational drug design]] | ||
[[Category: Serine protease activation]] | [[Category: Serine protease activation]] | ||
[[Category: Substrate-assisted catalysis]] | [[Category: Substrate-assisted catalysis]] | ||
Revision as of 14:11, 25 July 2012
Crystal structure of uninhibited factor VIIaCrystal structure of uninhibited factor VIIa
Template:ABSTRACT PUBMED 12225752
About this StructureAbout this Structure
1klj is a 2 chain structure of Factor VIIa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Sichler K, Banner DW, D'Arcy A, Hopfner KP, Huber R, Bode W, Kresse GB, Kopetzki E, Brandstetter H. Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions. J Mol Biol. 2002 Sep 20;322(3):591-603. PMID:12225752
- ↑ Dullweber F, Stubbs MT, Musil D, Sturzebecher J, Klebe G. Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition. J Mol Biol. 2001 Oct 26;313(3):593-614. PMID:11676542 doi:http://dx.doi.org/10.1006/jmbi.2001.5062