1adv: Difference between revisions

Revision as of 12:43, 21 February 2008

EARLY E2A DNA-BINDING PROTEIN

OverviewOverview

A second crystal form of the C-terminal domain of the adenovirus single-stranded DNA binding protein crystallizes in space group P2(1)2(1)2(1) with a=61.0 angstrom, b=91.2 angstrom and c=149.4 angstrom. The crystals contain two molecules per asymmetric unit and diffract to a maximum resolution of 3.0 angstrom. The crystal is composed of infinite chains of molecules along the crystallographic 2(1) axis parallel to c. The principal intermolecular interaction is a hooking of the C-terminal 17 residues of one molecule onto the next molecule in the protein chain. Adjacent molecules in the chain are rotated approximately 90 degrees with respect to their neighbours. The difference in relative orientation of adjacent molecules between the two crystal forms of the protein implies a degree of flexibility in the protein chain that would facilitate DNA binding.

About this StructureAbout this Structure

1ADV is a Single protein structure of sequence from Human adenovirus 11 with as ligand. Full crystallographic information is available from OCA.

ReferenceReference

Alternative arrangements of the protein chain are possible for the adenovirus single-stranded DNA binding protein., Kanellopoulos PN, Tsernoglou D, van der Vliet PC, Tucker PA, J Mol Biol. 1996 Mar 22;257(1):1-8. PMID:8632448

Page seeded by OCA on Thu Feb 21 11:43:24 2008

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OCA

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 '''EARLY E2A DNA-BINDING PROTEIN'''<br />
 ==Overview==
-A second crystal form of the C-terminal domain of the adenovirus, single-stranded DNA binding protein crystallizes in space group, P2(1)2(1)2(1) with a=61.0 angstrom, b=91.2 angstrom and c=149.4 angstrom., The crystals contain two molecules per asymmetric unit and diffract to a, maximum resolution of 3.0 angstrom. The crystal is composed of infinite, chains of molecules along the crystallographic 2(1) axis parallel to c., The principal intermolecular interaction is a hooking of the C-terminal 17, residues of one molecule onto the next molecule in the protein chain., Adjacent molecules in the chain are rotated approximately 90 degrees with, respect to their neighbours. The difference in relative orientation of, adjacent molecules between the two crystal forms of the protein implies a, degree of flexibility in the protein chain that would facilitate DNA, binding.
+A second crystal form of the C-terminal domain of the adenovirus single-stranded DNA binding protein crystallizes in space group P2(1)2(1)2(1) with a=61.0 angstrom, b=91.2 angstrom and c=149.4 angstrom. The crystals contain two molecules per asymmetric unit and diffract to a maximum resolution of 3.0 angstrom. The crystal is composed of infinite chains of molecules along the crystallographic 2(1) axis parallel to c. The principal intermolecular interaction is a hooking of the C-terminal 17 residues of one molecule onto the next molecule in the protein chain. Adjacent molecules in the chain are rotated approximately 90 degrees with respect to their neighbours. The difference in relative orientation of adjacent molecules between the two crystal forms of the protein implies a degree of flexibility in the protein chain that would facilitate DNA binding.
 ==About this Structure==
-ADV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_adenovirus_11 Human adenovirus 11] with ZN as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1ADV OCA].
+ADV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_adenovirus_11 Human adenovirus 11] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ADV OCA].
 ==Reference==
@@ Line 13: / Line 13: @@
 [[Category: Human adenovirus 11]]
 [[Category: Single protein]]
-[[Category: Kanellopoulos, P.N.]]
+[[Category: Kanellopoulos, P N.]]
 [[Category: Tsernoglou, D.]]
-[[Category: Tucker, P.A.]]
+[[Category: Tucker, P A.]]
-[[Category: Vliet, P.C.Van.Der.]]
+[[Category: Vliet, P C.Van Der.]]
 [[Category: ZN]]
 [[Category: dna-binding protein]]
 [[Category: ssdna binding protein]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 10:47:02 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:43:24 2008''