3ras: Difference between revisions

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[[Image:3ras.png|left|200px]]
[[Image:3ras.png|left|200px]]


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{{STRUCTURE_3ras|  PDB=3ras  |  SCENE=  }}  
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===Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with a lipophilic phosphonate inhibitor===
===Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with a lipophilic phosphonate inhibitor===


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[[Category: Isoprene biosynthesis]]
[[Category: Isoprene biosynthesis]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase-inhibitor complex]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

Revision as of 09:13, 25 July 2012

File:3ras.png

Template:STRUCTURE 3ras

Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with a lipophilic phosphonate inhibitorCrystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with a lipophilic phosphonate inhibitor

Template:ABSTRACT PUBMED 21561155

About this StructureAbout this Structure

3ras is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Deng L, Diao J, Chen P, Pujari V, Yao Y, Cheng G, Crick DC, Prasad BV, Song Y. Inhibition of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase by Lipophilic Phosphonates: SAR, QSAR and Crystallographic Studies. J Med Chem. 2011 May 11. PMID:21561155 doi:10.1021/jm200363d

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OCA