1a3n: Difference between revisions

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OCA

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-[[Image:1a3n.gif|left|200px]]<br />
+[[Image:1a3n.gif|left|200px]]<br /><applet load="1a3n" size="350" color="white" frame="true" align="right" spinBox="true"
-<applet load="1a3n" size="450" color="white" frame="true" align="right" spinBox="true"
 caption="1a3n, resolution 1.8&Aring;" />
 '''DEOXY HUMAN HEMOGLOBIN'''<br />
 ==Overview==
-The structures of deoxy human haemoglobin and an artificial mutant, (Tyralpha42--&gt;His) have been solved at 120 K. While overall agreement, between these structures and others in the PDB is very good, certain side, chains are found to be shifted, absent from the electron-density map or in, different rotamers. Non-crystallographic symmetry (NCS) is very well, obeyed in the native protein, but not around the site of the changed, residue in the mutant. NCS is also not obeyed by the water molecule, invariably found in the alpha-chain haem pocket in room-temperature, crystal structures of haemoglobin. At 120 K, this water molecule, disappears from one alpha chain in the asymmetric unit but not the other.
+The structures of deoxy human haemoglobin and an artificial mutant (Tyralpha42--&gt;His) have been solved at 120 K. While overall agreement between these structures and others in the PDB is very good, certain side chains are found to be shifted, absent from the electron-density map or in different rotamers. Non-crystallographic symmetry (NCS) is very well obeyed in the native protein, but not around the site of the changed residue in the mutant. NCS is also not obeyed by the water molecule invariably found in the alpha-chain haem pocket in room-temperature crystal structures of haemoglobin. At 120 K, this water molecule disappears from one alpha chain in the asymmetric unit but not the other.
 ==Disease==
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 ==About this Structure==
-A3N is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with HEM as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1A3N OCA].
+A3N is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=HEM:'>HEM</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A3N OCA].
 ==Reference==
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 [[Category: respiratory protein]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 15:55:09 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:40:28 2008''