3um5: Difference between revisions

Revision as of 08:24, 18 July 2012

3um5 is a 2 chain structure with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.

↑ Vanichtanankul J, Taweechai S, Uttamapinant C, Chitnumsub P, Vilaivan T, Yuthavong Y, Kamchonwongpaisan S. Combined Spatial Limitation around Residues 16 and 108 of Plasmodium falciparum Dihydrofolate Reductase Explains Resistance to Cycloguanil. Antimicrob Agents Chemother. 2012 Jul;56(7):3928-35. Epub 2012 Apr 23. PMID:22526319 doi:10.1128/AAC.00301-12

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-'''Unreleased structure'''
+[[Image:3um5.jpg|left|200px]]
-The entry 3um5 is ON HOLD  until Paper Publication
+{{STRUCTURE_3um5|  PDB=3um5  |  SCENE=  }}
-Authors: Vanichtanankul, J., Kamchonwongpaisan, S., Chitnumsub, P., Yuthavong, Y.
+===Double mutant (A16V+S108T) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS-T9/94) complexed with pyrimethamine, NADPH, and dUMP===
-Description: Double mutant (A16V+S108T) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS-T9/94) complexed with pyrimethamine, NADPH, and dUMP
+{{ABSTRACT_PUBMED_22526319}}
+==About this Structure==
+[[3um5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UM5 OCA].
+==Reference==
+<ref group="xtra">PMID:022526319</ref><references group="xtra"/>
+[[Category: Plasmodium falciparum]]
+[[Category: Chitnumsub, P.]]
+[[Category: Kamchonwongpaisan, S.]]
+[[Category: Vanichtanankul, J.]]
+[[Category: Yuthavong, Y.]]
+[[Category: Antifolate]]
+[[Category: Dump]]
+[[Category: Malarial dhfr-t]]
+[[Category: Napdh]]
+[[Category: Oxidoreductase]]
+[[Category: Pyrimethamine]]
+[[Category: Transferase-inhibitor complex]]