1dxw: Difference between revisions

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Revision as of 07:43, 27 June 2012

File:1dxw.png

Template:STRUCTURE 1dxw

structure of hetero complex of non structural protein (NS) of hepatitis C virus (HCV) and synthetic peptidic compoundstructure of hetero complex of non structural protein (NS) of hepatitis C virus (HCV) and synthetic peptidic compound

Template:ABSTRACT PUBMED 10716920

About this StructureAbout this Structure

1dxw is a 1 chain structure with sequence from Hepatitis c virus. Full experimental information is available from OCA.

ReferenceReference

^{[xtra 1]}^{[xtra 2]}^{[xtra 3]}^{[xtra 4]}

↑ Barbato G, Cicero DO, Cordier F, Narjes F, Gerlach B, Sambucini S, Grzesiek S, Matassa VG, De Francesco R, Bazzo R. Inhibitor binding induces active site stabilization of the HCV NS3 protein serine protease domain. EMBO J. 2000 Mar 15;19(6):1195-206. PMID:10716920 doi:10.1093/emboj/19.6.1195
↑ Barbato G, Cicero DO, Nardi MC, Steinkuhler C, Cortese R, De Francesco R, Bazzo R. The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism. J Mol Biol. 1999 Jun 4;289(2):371-84. PMID:10366511 doi:10.1006/jmbi.1999.2745
↑ Cicero DO, Barbato G, Koch U, Ingallinella P, Bianchi E, Nardi MC, Steinkuhler C, Cortese R, Matassa V, De Francesco R, Pessi A, Bazzo R. Structural characterization of the interactions of optimized product inhibitors with the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein by NMR and modelling studies. J Mol Biol. 1999 Jun 4;289(2):385-96. PMID:10366512 doi:10.1006/jmbi.1999.2746
↑ Urbani A, Bazzo R, Nardi MC, Cicero DO, De Francesco R, Steinkuhler C, Barbato G. The metal binding site of the hepatitis C virus NS3 protease. A spectroscopic investigation. J Biol Chem. 1998 Jul 24;273(30):18760-9. PMID:9668049

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OCA

[1] Barbato G, Cicero DO, Cordier F, Narjes F, Gerlach B, Sambucini S, Grzesiek S, Matassa VG, De Francesco R, Bazzo R. Inhibitor binding induces active site stabilization of the HCV NS3 protein serine protease domain. EMBO J. 2000 Mar 15;19(6):1195-206. PMID:10716920 doi:10.1093/emboj/19.6.1195

[2] Barbato G, Cicero DO, Nardi MC, Steinkuhler C, Cortese R, De Francesco R, Bazzo R. The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism. J Mol Biol. 1999 Jun 4;289(2):371-84. PMID:10366511 doi:10.1006/jmbi.1999.2745

[3] Cicero DO, Barbato G, Koch U, Ingallinella P, Bianchi E, Nardi MC, Steinkuhler C, Cortese R, Matassa V, De Francesco R, Pessi A, Bazzo R. Structural characterization of the interactions of optimized product inhibitors with the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein by NMR and modelling studies. J Mol Biol. 1999 Jun 4;289(2):385-96. PMID:10366512 doi:10.1006/jmbi.1999.2746

[4] Urbani A, Bazzo R, Nardi MC, Cicero DO, De Francesco R, Steinkuhler C, Barbato G. The metal binding site of the hepatitis C virus NS3 protease. A spectroscopic investigation. J Biol Chem. 1998 Jul 24;273(30):18760-9. PMID:9668049

[xtra 1]

[xtra 2]

[xtra 3]

[xtra 4]

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 [[Image:1dxw.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_1dxw", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_1dxw|  PDB=1dxw  |  SCENE=  }}
-===STRUCTURE OF HETERO COMPLEX OF NON STRUCTURAL PROTEIN (NS) OF HEPATITIS C VIRUS (HCV) AND SYNTHETIC PEPTIDIC COMPOUND===
+===structure of hetero complex of non structural protein (NS) of hepatitis C virus (HCV) and synthetic peptidic compound===
-<!--
-The line below this paragraph, {{ABSTRACT_PUBMED_10716920}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 10716920 is the PubMed ID number.
--->
 {{ABSTRACT_PUBMED_10716920}}
 ==About this Structure==
-[[1dxw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DXW OCA].
+[[1dxw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DXW OCA].
 ==Reference==
-<ref group="xtra">PMID:10716920</ref><ref group="xtra">PMID:10366511</ref><ref group="xtra">PMID:10366512</ref><ref group="xtra">PMID:9668049</ref><references group="xtra"/>
+<ref group="xtra">PMID:010716920</ref><ref group="xtra">PMID:010366511</ref><ref group="xtra">PMID:010366512</ref><ref group="xtra">PMID:009668049</ref><references group="xtra"/>
-[[Category: Viruses]]
+[[Category: Hepatitis c virus]]
 [[Category: Barbato, G.]]
 [[Category: Bazzo, R.]]
@@ Line 35: / Line 24: @@
 [[Category: Sambucini, S.]]
 [[Category: Hepatitis c virus]]
-[[Category: Hydrolase]]
+[[Category: Hydrolase-hydrolase inhibitor complex]]
-[[Category: Hydrolase/hydrolase inhibitor]]
 [[Category: Non structural protein]]
 [[Category: Serine protease]]

1dxw: Difference between revisions

Revision as of 07:43, 27 June 2012

structure of hetero complex of non structural protein (NS) of hepatitis C virus (HCV) and synthetic peptidic compoundstructure of hetero complex of non structural protein (NS) of hepatitis C virus (HCV) and synthetic peptidic compound

About this StructureAbout this Structure

ReferenceReference

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