1urr: Difference between revisions
New page: left|200px<br /> <applet load="1urr" size="450" color="white" frame="true" align="right" spinBox="true" caption="1urr, resolution 1.50Å" /> '''A NOVEL DROSOPHILA ... |
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==About this Structure== | ==About this Structure== | ||
1URR is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]] with GOL as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.7 3.6.1.7]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1URR OCA]]. | 1URR is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]] with GOL as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/Acylphosphatase Acylphosphatase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.7 3.6.1.7]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1URR OCA]]. | ||
==Reference== | ==Reference== | ||
Three-dimensional structural characterization of a novel Drosophila melanogaster acylphosphatase., Zuccotti S, Rosano C, Ramazzotti M, Degl'Innocenti D, Stefani M, Manao G, Bolognesi M, Acta Crystallogr D Biol Crystallogr. 2004 Jun;60(Pt 6):1177-9. Epub 2004, May 21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15159593 15159593] | Three-dimensional structural characterization of a novel Drosophila melanogaster acylphosphatase., Zuccotti S, Rosano C, Ramazzotti M, Degl'Innocenti D, Stefani M, Manao G, Bolognesi M, Acta Crystallogr D Biol Crystallogr. 2004 Jun;60(Pt 6):1177-9. Epub 2004, May 21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15159593 15159593] | ||
[[Category: Acylphosphatase]] | |||
[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: enzyme]] | [[Category: enzyme]] | ||
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Revision as of 14:20, 30 October 2007
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A NOVEL DROSOPHILA MELANOGASTER ACYLPHOSPHATASE (ACPDRO2)
OverviewOverview
Analysis of the Drosophila melanogaster EST database led to the discovery, and cloning of a novel acylphosphatase. The CG18505 gene coding for a new, enzyme (AcPDro2) is clearly distinct from the previously described, CG16870Acyp gene, which also codes for a D. melanogaster acylphosphatase, (AcPDro). The putative catalytic residues, together with residues held to, stabilize the acylphosphatase fold, are conserved in the two encoded, proteins. Crystals of AcPDro2, which belong to the trigonal space group, P3(1)21, with unit-cell parameters a = b = 45.8, c = 98.6 angstroms, gamma, = 120 degrees, allowed the solution of the protein structure by molecular, replacement and its refinement to 1.5 angstroms resolution. The AcPDro2, active-site structure is discussed.
About this StructureAbout this Structure
1URR is a [Single protein] structure of sequence from [Drosophila melanogaster] with GOL as [ligand]. Active as [Acylphosphatase], with EC number [3.6.1.7]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
ReferenceReference
Three-dimensional structural characterization of a novel Drosophila melanogaster acylphosphatase., Zuccotti S, Rosano C, Ramazzotti M, Degl'Innocenti D, Stefani M, Manao G, Bolognesi M, Acta Crystallogr D Biol Crystallogr. 2004 Jun;60(Pt 6):1177-9. Epub 2004, May 21. PMID:15159593
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