Lactate Dehydrogenase: Difference between revisions
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==3D structures of lactate dehydrogenase== | ==3D structures of lactate dehydrogenase== | ||
''Updated | ''Updated June 2012'' | ||
[[2e37]], [[2v6m]] – TtL-LDH – ''Thermus thermophilus''<BR /> | [[2e37]], [[2v6m]] – TtL-LDH – ''Thermus thermophilus''<BR /> | ||
[[2xxe]] – TtL-LDH (mutant) <BR /> | [[2xxe]], [[3zzn]], [[4a73]]– TtL-LDH (mutant) <BR /> | ||
[[2x8l]], [[1ceq]] – PfL-LDH – ''Plasmodium falciparum''<BR /> | [[2x8l]], [[1ceq]] – PfL-LDH – ''Plasmodium falciparum''<BR /> | ||
[[2zqy]], [[2zqz]], [[1llc]] – | [[2zqy]], [[2zqz]], [[1llc]] – LcL-LDH – ''Lactobacillus casei''<BR /> | ||
[[3d0o]] - SaL-LDH – ''Staphylococcus aureus''<BR /> | [[3d0o]] - SaL-LDH – ''Staphylococcus aureus''<BR /> | ||
[[2v65]] - L-LDH A chain – ''Champsocephalus gunnari''<BR /> | [[2v65]] - L-LDH A chain – ''Champsocephalus gunnari''<BR /> | ||
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[[1ldb]] - GsL-LDH – ''Geobacillus stearothermophilus''<BR /> | [[1ldb]] - GsL-LDH – ''Geobacillus stearothermophilus''<BR /> | ||
[[1ldm]], [[6ldh]], [[8ldh]] – sdM4-LDH – spiny dogfish<BR /> | [[1ldm]], [[6ldh]], [[8ldh]] – sdM4-LDH – spiny dogfish<BR /> | ||
[[2ldx]] – C4-LDH - mouse | [[2ldx]] – C4-LDH - mouse<br /> | ||
[[3pqe]] – BsL-LDH (mutant) – ''Bacillus subtilis'' | |||
===L-LDH from yeast (cytochrome b2)=== | ===L-LDH from yeast (cytochrome b2)=== | ||
[[1lco]] | [[1kbj]] - LDH FMN-binding domain | ||
[[ | [[1sze]], [[1lco]], [[2oz0]] - LDH FMN-binding domain (mutant) <br /> | ||
[[1szf]] - LDH | [[1kbi]] - LDH FMN-binding domain + pyruvate<br /> | ||
[[1szf]], [[1ldc]] - LDH FMN-binding domain (mutant) + pyruvate<br /> | |||
[[1szg]] - LDH FMN-binding domain + sulfo-FMN<br /> | |||
[[3ks0]] - LDH residues 86-180 + flavocytochrome b2 heme domain + FAB B2B4 | [[3ks0]] - LDH residues 86-180 + flavocytochrome b2 heme domain + FAB B2B4 | ||
===LDH binary complex=== | ===L-LDH binary complex=== | ||
[[2ydn]] – PfL-LDH + bicine<BR /> | [[2ydn]] – PfL-LDH + bicine<BR /> | ||
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[[2a94]], [[2aa3]] - PvL-LDH + NAD-analog<br /> | [[2a94]], [[2aa3]] - PvL-LDH + NAD-analog<br /> | ||
[[1u4o]], [[1u4s]], [[1u5a]], [[1xiv]] – PfL-LDH + inhibitor<BR /> | [[1u4o]], [[1u4s]], [[1u5a]], [[1xiv]] – PfL-LDH + inhibitor<BR /> | ||
[[2xxb]] – TtL-LDH (mutant) + AMP | [[2xxb]] – TtL-LDH (mutant) + AMP<br /> | ||
[[3pqf]] – BsL-LDH (mutant) + NAD<br /> | |||
[[3vkv]] - LcLDH + fructose-bisphosphate<br /> | |||
[[4aj1]], [[4aj2]], [[4aj4]], [[4aje]], [[4ajh]], [[4aji]], [[4ajj]], [[4ajk]], [[4aj]]l, [[4ajn]], [[4ajo]], [[4al4]] – LDH α chain + inhibitor – rat<br /> | |||
[[4ajp]] – hLDH α chain + inhibitor - human | |||
===L-LDH ternary complex with inhibitor=== | ===L-LDH ternary complex with inhibitor=== | ||
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[[3h3f]] – L-LDH A chain + oxamate + NAD – rabbit<BR /> | [[3h3f]] – L-LDH A chain + oxamate + NAD – rabbit<BR /> | ||
[[2fnz]] - CpLDH + oxamate + NAD<BR /> | [[2fnz]] - CpLDH + oxamate + NAD<BR /> | ||
[[1t2f]] - hL-LDH B chain + azole derivative + NAD | [[1t2f]] - hL-LDH B chain + azole derivative + NAD <BR /> | ||
[[1i0z]] - hL-LDH H chain + oxamate + NAD<BR /> | [[1i0z]] - hL-LDH H chain + oxamate + NAD<BR /> | ||
[[1i10]] - hL-LDH M chain + oxamate + NAD<BR /> | [[1i10]] - hL-LDH M chain + oxamate + NAD<BR /> | ||
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[[5ldh]] - pLDH + citrate + NAD-analog<br /> | [[5ldh]] - pLDH + citrate + NAD-analog<br /> | ||
[[3ldh]] - sdLDH + pyruvate + NAD<BR /> | [[3ldh]] - sdLDH + pyruvate + NAD<BR /> | ||
[[3pqd]] - BsLDH + fructose-bisphosphate + NAD | |||
===D-LDH=== | ===D-LDH=== | ||
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[[1x0a]], [[1vbi]] – TtL-LDH II | [[1x0a]], [[1vbi]] – TtL-LDH II | ||
===L-Lactate/malate dehydrogenase=== | |||
[[1hye]], [[1hyg]] – L-LDH/MDH – ''Methanocaldococcus jannaschi'' | |||