Aldehyde dehydrogenase: Difference between revisions
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[[Image:1nzx.png|left|200px|thumb|Crystal Structure of Aldehyde dehydrogenase, [[1nzx]]]] | [[Image:1nzx.png|left|200px|thumb|Crystal Structure of Aldehyde dehydrogenase, [[1nzx]]]] | ||
{{STRUCTURE_1nzx| PDB=1nzx | SIZE= | {{STRUCTURE_1nzx| PDB=1nzx | SIZE=400| SCENE=Aldehyde_dehydrogenase/Aldh/1 |right|CAPTION=Human aldehyde hydrogenase class 2 complex with NAD , [[1nzx]] }} | ||
'''Aldehyde dehydrogenase''' (ALDH) converts aldehydes to carboxylic acids while reducing NAD+ to NADH. In mammals there are 3 classes of ALDH and each contain constitutive and inducible forms. Class 1 is cytosolic; class 2 mitochondrial; class 3 found in tumors, stomach and cornea. ALDH family 7 member A1 is known as antiquitin and functions in the detoxification of aldehydes. Glyceraldehyde-3-phophate (G3P)-ALDH is called GAPDH. | '''Aldehyde dehydrogenase''' (ALDH) converts aldehydes to carboxylic acids while reducing NAD+ to NADH. In mammals there are 3 classes of ALDH and each contain constitutive and inducible forms. Class 1 is cytosolic; class 2 mitochondrial; class 3 found in tumors, stomach and cornea. ALDH family 7 member A1 is known as antiquitin and functions in the detoxification of aldehydes. Glyceraldehyde-3-phophate (G3P)-ALDH is called GAPDH. | ||