4epr: Difference between revisions

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'''Unreleased structure'''
[[Image:4epr.jpg|left|200px]]


The entry 4epr is ON HOLD until Paper Publication
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{{STRUCTURE_4epr|  PDB=4epr  |  SCENE=  }}


Authors: Sun, Q, Burke, J.P., Phan, J., Burns, M.C., Olejniczak, E.T., Waterson, A.G., Lee, T., Rossanese, O.W., Fesik, S.W.
===Crystal structure of KRas-GDP (G12D)===


Description: Crystal structure of KRas-GDP (G12D)
 
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{{ABSTRACT_PUBMED_22566140}}
 
==About this Structure==
[[4epr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EPR OCA].
 
==Reference==
<ref group="xtra">PMID:022566140</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Small monomeric GTPase]]
[[Category: Burke, J P.]]
[[Category: Burns, M C.]]
[[Category: Fesik, S W.]]
[[Category: Lee, T.]]
[[Category: Olejniczak, E T.]]
[[Category: Phan, J.]]
[[Category: Rossanese, O W.]]
[[Category: Sun, Q]]
[[Category: Waterson, A G.]]
[[Category: Binder]]
[[Category: Closed conformation]]
[[Category: Gtp-binding protein]]
[[Category: Hydrolase]]
[[Category: Inhibitor of sos-mediated activation]]
[[Category: Kra]]
[[Category: Oncogene]]
[[Category: P21]]

Revision as of 09:01, 23 May 2012

File:4epr.jpg

Template:STRUCTURE 4epr

Crystal structure of KRas-GDP (G12D)Crystal structure of KRas-GDP (G12D)

Template:ABSTRACT PUBMED 22566140

About this StructureAbout this Structure

4epr is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Sun Q, Burke JP, Phan J, Burns MC, Olejniczak ET, Waterson AG, Lee T, Rossanese OW, Fesik SW. Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation. Angew Chem Int Ed Engl. 2012 May 8. doi: 10.1002/anie.201201358. PMID:22566140 doi:10.1002/anie.201201358

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