1gt3: Difference between revisions
New page: left|200px<br /> <applet load="1gt3" size="450" color="white" frame="true" align="right" spinBox="true" caption="1gt3, resolution 1.8Å" /> '''COMPLEX OF BOVINE OD... |
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==About this Structure== | ==About this Structure== | ||
1GT3 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]] with DHM and 3OL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GT3 OCA]]. | 1GT3 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]] with DHM and 3OL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: DHA. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GT3 OCA]]. | ||
==Reference== | ==Reference== | ||
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[[Category: lipocalin]] | [[Category: lipocalin]] | ||
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Revision as of 14:12, 30 October 2007
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COMPLEX OF BOVINE ODORANT BINDING PROTEIN WITH DIHYDROMYRCENOL
OverviewOverview
The structure of bovine odorant-binding protein (bOBP) revealed a striking, feature of a dimer formed by domain swapping [Tegoni, M., Ramoni, R., Bignetti, E., Spinelli, S. & Cambillau, C. (1996) Nat. Struct. Biol.3, 863-867; Bianchet, M.A., Bains, G., Pelosi, P., Pevsner, J., Snyder, S.H., Monaco, H.L. & Amzel, L.M. (1996) Nat. Struct. Biol.3, 934-939] and the, presence of a naturally occuring ligand [Ramoni, R., Vincent, F., Grolli, S., Conti, V., Malosse, C., Boyer, F.D., Nagnan-Le Meillour, P., Spinelli, S., Cambillau, C. & Tegoni, M. (2001) J. Biol. Chem.276, 7150-7155]. These, features led us to investigate the binding of odorant molecules with bOBP, in solution and in the crystal. The behavior of odorant molecules in bOBP, resembles that observed with porcine OBP ... [(full description)]
About this StructureAbout this Structure
1GT3 is a [Single protein] structure of sequence from [Bos taurus] with DHM and 3OL as [ligands]. Structure known Active Site: DHA. Full crystallographic information is available from [OCA].
ReferenceReference
Crystal structures of bovine odorant-binding protein in complex with odorant molecules., Vincent F, Ramoni R, Spinelli S, Grolli S, Tegoni M, Cambillau C, Eur J Biochem. 2004 Oct;271(19):3832-42. PMID:15373829
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