MAP kinase phosphatase: Difference between revisions
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[[Image:1hzm.png|left|200px|thumb|Crystal Structure of MAP kinase phosphatase [[1hzm]]]] | [[Image:1hzm.png|left|200px|thumb|Crystal Structure of MAP kinase phosphatase [[1hzm]]]] | ||
{{STRUCTURE_1hzm| PDB=1hzm | SIZE= | {{STRUCTURE_1hzm| PDB=1hzm | SIZE=400| SCENE=MAP_kinase_phosphatase/Cv/1 |right|CAPTION=MAP kinase phosphatase 3 [[1hzm]] }} | ||
{{TOC limit|limit=2}} | {{TOC limit|limit=2}} | ||
Revision as of 09:42, 16 May 2012
MAP kinase phosphatase (MKP) or Dual specificity phosphatase (DUSP) are phosphatases which reverse the activation of MAP kinases by dephosphorylating tyrosine or threonine residues.
3D Structures of MAP kinase phosphatase3D Structures of MAP kinase phosphatase
3ezz – hMKP-2 (mutant) or DUSP-HVH2 - human
2fys - hMKP-3 peptide or DUSP-5 +rMAP kinase – rat
1hzm - hMKP-3 or DUSP-5
1mkp - hMKP-3 or DUSP-5 (mutant)
3lj8 – hMKP-4
2ouc, 2oud, 1zzw - hMKP-5 or DUSP-10
2wgp – hMKP-6 or DUSP-14
2vsw - hMKP-7 or DUSP-16
1j4x – hDUSP-3 (mutant)+peptide
2g6z – hDUSP-5
2rf6, 2q05 – DUSP – Vaccinia virus