4a6c: Difference between revisions

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'''Unreleased structure'''
[[Image:4a6c.jpg|left|200px]]


The entry 4a6c is ON HOLD
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{{STRUCTURE_4a6c|  PDB=4a6c |  SCENE=  }}


Authors: Wu, X., Ohrngren, P., Joshi, A.A., Trejos, A., Persson, M., Unge, J., Arvela, R.K., Wallberg, H., Vrang, L., Rosenquist, A., Samuelsson, B., Unge, T., Larhed, M.
===Stereoselective Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Lactam Based HIV-1 Protease Inhibitors===


Description: Stereoselective Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Lactam Based HIV-1 Protease Inhibitors
 
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{{ABSTRACT_PUBMED_22376008}}
 
==About this Structure==
[[4a6c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus Human immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A6C OCA].
 
==Reference==
<ref group="xtra">PMID:022376008</ref><references group="xtra"/>
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus]]
[[Category: Arvela, R K.]]
[[Category: Joshi, A A.]]
[[Category: Larhed, M.]]
[[Category: Ohrngren, P.]]
[[Category: Persson, M.]]
[[Category: Rosenquist, A.]]
[[Category: Samuelsson, B B.]]
[[Category: Trejos, A.]]
[[Category: Unge, J.]]
[[Category: Vrang, L.]]
[[Category: Wallberg, H.]]
[[Category: Wu, X.]]
[[Category: Gamma-butyrol-lactam]]
[[Category: Hydrolase]]

Revision as of 12:14, 9 May 2012

File:4a6c.jpg

Template:STRUCTURE 4a6c

Stereoselective Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Lactam Based HIV-1 Protease InhibitorsStereoselective Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Lactam Based HIV-1 Protease Inhibitors

Template:ABSTRACT PUBMED 22376008

About this StructureAbout this Structure

4a6c is a 2 chain structure with sequence from Human immunodeficiency virus. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Wu X, Ohrngren P, Joshi AA, Trejos A, Persson M, Arvela RK, Wallberg H, Vrang L, Rosenquist A, Samuelsson BB, Unge J, Larhed M. Synthesis, X-ray analysis, and biological evaluation of a new class of stereopure lactam-based HIV-1 protease inhibitors. J Med Chem. 2012 Mar 22;55(6):2724-36. Epub 2012 Mar 13. PMID:22376008 doi:10.1021/jm201620t

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