Human growth hormone: Difference between revisions

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 Mature hGH travels through the bloodstream and interacts with a specific hGH-receptor on the surface of various cells, including muscle, bone, and cartilage. Binding of hGH to its receptor causes dimerization and signal transduction, which ultimately stimulates cellular division.  HGH also indirectly influences growth by stimulating the liver to produce additional growth factors, such as insulin-like growth factor-1. Synthetic versions of hGH produced by recombinant DNA technology are used to treat growth disorders associated with hGH deficiencies.
-==About this Structure==
-HGU is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The April 2004 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Growth Hormone''  by Shuchismita Dutta and David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2004_4 10.2210/rcsb_pdb/mom_2004_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HGU OCA].
-[[Category: Growth Hormone]]
-[[Category: Homo sapiens]]
-[[Category: RCSB PDB Molecule of the Month]]
-[[Category: Chantalat, L.]]
-[[Category: Jones, N.]]
-[[Category: Korber, F.]]
-[[Category: Navaza, J.]]
-[[Category: Pavlovsky, A G.]]
-[[Category: Hormone]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 21 09:03:49 2010''
 ==Location in the Body==