Sandbox Reserved 479: Difference between revisions
No edit summary |
|||
| Line 9: | Line 9: | ||
==Structure== | ==Structure== | ||
Myosin is a 520 kDa hexamer, or a '''hexa-oligomer''' (6 subunit) structure. It is comprised of two heavy chains (weighing 220 kDa each) and 4 light chains (weighing 20 kDa each).<ref name="CHEM43">[http://www.cs.stedwards.edu/chem/Chemistry/CHEM43/CHEM43/Myosin/STRUCT~1.HTM]</ref> | Myosin is a 520 kDa hexamer, or a '''hexa-oligomer''' (6 subunit) structure. It is comprised of two heavy chains (weighing 220 kDa each) and 4 light chains (weighing 20 kDa each).<ref name="CHEM43">[http://www.cs.stedwards.edu/chem/Chemistry/CHEM43/CHEM43/Myosin/STRUCT~1.HTM]</ref> The 2-D structure below of myosin II shows 7 stranded beta sheet and the ATP-binding site between the middle and N-terminal of the protein. The C-terminal contains the light chains (regulatory domain) and acts as the lever arm to enhance the converter domain's rotational movements. | ||
[[Image:Mds1.png]] | [[Image:Mds1.png]] | ||