4ago: Difference between revisions
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[[Image:4ago. | [[Image:4ago.png|left|200px]] | ||
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The line below this paragraph, {{ | The line below this paragraph, {{ABSTRACT_PUBMED_22439615}}, adds the Publication Abstract to the page | ||
(as it appears on PubMed at http://www.pubmed.gov), where | (as it appears on PubMed at http://www.pubmed.gov), where 22439615 is the PubMed ID number. | ||
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{{ | {{ABSTRACT_PUBMED_22439615}} | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:017015838</ref><references group="xtra"/> | <ref group="xtra">PMID:022439615</ref><ref group="xtra">PMID:017015838</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Boeckler, F M.]] | [[Category: Boeckler, F M.]] | ||
Revision as of 21:24, 2 May 2012
Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5174Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5174
Template:ABSTRACT PUBMED 22439615
About this StructureAbout this Structure
4ago is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Wilcken R, Liu X, Zimmermann MO, Rutherford TJ, Fersht AR, Joerger AC, Boeckler FM. Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant p53. J Am Chem Soc. 2012 Apr 18;134(15):6810-8. Epub 2012 Apr 5. PMID:22439615 doi:10.1021/ja301056a
- ↑ Joerger AC, Ang HC, Fersht AR. Structural basis for understanding oncogenic p53 mutations and designing rescue drugs. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:17015838