Interferon: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:InterferonSignalingPathway.png|525px|right|thumb|Interferon Pathway<ref>[http://www.jbc.org/content/282/28/20045.full?sid=cbf08059-44d4-4957-8ea7-0351cab9c2ac] Samuel, C.E. "Interferons, Interferon Receptors, Signal Transducer and Transcriptional Activators, and Inteferon Regulatory Factors." ''J Biol Chem'' 2007 282: 20045-20046. First Published on May 14, 2007, doi:10.1074/jbc.R700025200</ref>]] | |||
<StructureSection load='2hym' size='500' side='right' caption='Click on the green links to the left to view the structural aspects of interferons. PDB ID: [[2hym]])' scene='Interferons/Interferonaandreceptor/2'> | <StructureSection load='2hym' size='500' side='right' caption='Click on the green links to the left to view the structural aspects of interferons. PDB ID: [[2hym]])' scene='Interferons/Interferonaandreceptor/2'> | ||
==Interferon-β== | ==Interferon-β== | ||
Revision as of 05:22, 22 April 2012
Interferon-βis a protein growth factor that stimulates an antiviral defense. Its encoding gene is one of only two known vertebrate structural genes that lacks introns.[2] Interferon-β is a relatively simple biological response modifier, with several . It consists of five , as well as multiple interconnecting . Helices A, B and D run , and helices C and E run to the other three helices, but to one another. Helix A consists of residues 6-23; Helix B consists of residues 49-65; Helix C consists of residues 77-91; Helix D consists of residues 112-131; and Helix E consists of residues 135-155.[3][4] Interferon-αInterferon-γ |
| ||||||||||
A comparative representation of three interferonsA comparative representation of three interferons
|
|
|
Synchronize the three applets showing interferons alpha, beta, and gamma by clicking the checkbox