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{{STRUCTURE_3vnt| PDB=3vnt | SCENE= }} | |||
===Crystal Structure of the Kinase domain of Human VEGFR2 with a [1,3]thiazolo[5,4-b]pyridine derivative=== | |||
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{{ABSTRACT_PUBMED_22376051}} | |||
==About this Structure== | |||
[[3vnt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VNT OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:022376051</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Receptor protein-tyrosine kinase]] | |||
[[Category: Oki, H.]] | |||
[[Category: Kinase domain]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||
[[Category: Tyrosin-protein kinase]] | |||
[[Category: Vegfr2]] | |||
Revision as of 09:57, 11 April 2012
Crystal Structure of the Kinase domain of Human VEGFR2 with a [1,3]thiazolo[5,4-b]pyridine derivativeCrystal Structure of the Kinase domain of Human VEGFR2 with a [1,3]thiazolo[5,4-b]pyridine derivative
Template:ABSTRACT PUBMED 22376051
About this StructureAbout this Structure
3vnt is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Okaniwa M, Hirose M, Imada T, Ohashi T, Hayashi Y, Miyazaki T, Arita T, Yabuki M, Kakoi K, Kato J, Takagi T, Kawamoto T, Yao S, Sumita A, Tsutsumi S, Tottori T, Oki H, Sang BC, Yano J, Aertgeerts K, Yoshida S, Ishikawa T. Design and Synthesis of Novel DFG-Out RAF/Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Inhibitors. 1. Exploration of [5,6]-Fused Bicyclic Scaffolds. J Med Chem. 2012 Mar 14. PMID:22376051 doi:10.1021/jm300126x